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PEP005

Known as: PEP 005, PEP-005 
 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Although anti-retroviral therapy (ART) is highly effective in suppressing HIV replication, it fails to eradicate the virus from… Expand
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Highly Cited
2010
Highly Cited
2010
OBJECTIVES To evaluate the safety of two applications of PEP005 (ingenol mebutate) gel in superficial basal cell carcinoma… Expand
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Highly Cited
2010
Highly Cited
2010
Ingenol-3-angelate (Ing3A), extracted from Euphorbia peplus, is currently in clinical trials for eradicating basal cell carcinoma… Expand
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2010
2010
The diterpene ester ingenol-3-angelate (referred to as PEP005) is derived from the plant Euphorbia peplus. Crude euphorbia… Expand
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Highly Cited
2009
Highly Cited
2009
The sap of the plant Euphorbia peplus is a traditional remedy for skin conditions, including actinic keratosis. The active… Expand
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Highly Cited
2008
Highly Cited
2008
PEP005 (ingenol-3-angelate) is a novel anticancer agent extracted from Euphorbia peplus that was previously shown to modulate… Expand
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2008
2008
The modes of action of the novel anti-skin tumor agent ingenol-3-angelate (PEP005) are incompletely understood. Crucially, the… Expand
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Highly Cited
2006
Highly Cited
2006
Harnessing neutrophils for the eradication of cancer cells remains an attractive but still controversial notion. In this study… Expand
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Highly Cited
2005
Highly Cited
2005
Ingenol 3-angelate (PEP005) is a selective small molecule activator of protein kinase C (PKC) extracted from the plant Euphorbia… Expand
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Highly Cited
2004
Highly Cited
2004
Options for skin cancer treatment currently include surgery, radiotherapy, topical chemotherapy, cryosurgery, curettage, and… Expand
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