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PECAM1 gene

Known as: CD31, platelet and endothelial cell adhesion molecule 1, PECAM1 
This gene is involved in several cellular processes such as: thrombosis, hemostasis, immunity, and inflammatory responses.
National Institutes of Health

Related topics

Related topics

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CD31 AntigensCell AdhesionLigand BindingPlatelet Endothelial Cell Adhesion Molecule, human

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PECAM1 wt Allele

Papers overview

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2013
2013
Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1
Members of the Plasmodium falciparum Erythrocyte Membrane protein 1 (PfEMP1) family expressed on the surface of malaria-infected… 
Highly Cited
2003
Highly Cited
2003
CD31 Regulates Direction and Rate of Neutrophil Migration over and under Endothelial Cells
Mechanisms guiding migration of neutrophils through endothelium are poorly understood. We showed previously that CD31-CD31… 
Highly Cited
2001
Highly Cited
2001
Inhibition of Antigen‐Specific T Cell Trafficking into the Central Nervous System via Blocking PECAM1/CD31 Molecule
Trafficking of antigen-specific T cells into the central nervous system (CNS) is an important initiating step in inflammation in… 
2001
2001
PECAM‐1 (CD31) engagement activates a phosphoinositide‐independent, nonspecific cation channel in endothelial cells
Platelet endothelial cell adhesion molecule‐1 (PECAM‐1) has been found to modulate a range of endothelial processes, including… 
Highly Cited
1999
Highly Cited
1999
CD31 (PECAM-1) exists as a dimer and is heavily N-glycosylated.
CD31 (PECAM-1) is a highly abundant cell surface glycoprotein expressed on hemopoietic and endothelial cells where it functions… 
Highly Cited
1998
Highly Cited
1998
Engagement of human PECAM-1 (CD31) on human endothelial cells increases intracellular calcium ion concentration and stimulates prostacyclin release.
Platelet-endothelial cell adhesion molecule-1 (PECAM-1) is a member of the immunoglobulin superfamily that plays a role in a… 
1996
1996
CD31‐triggered rearrangement of the actin cytoskeleton in human natural killer cells
In this report, we analyze whether CD31, also known as platelet‐endothelial cell adhesion molecule‐1 (PECAM‐1), can transduce an… 
Highly Cited
1994
Highly Cited
1994
Platelet alpha-granule and plasma membrane share two new components: CD9 and PECAM-1.
CD9 (p24) and PECAM1 (CD31) antigens are well-defined components of the platelet plasma membrane. Both are integral glycoproteins… 
Highly Cited
1993
Highly Cited
1993
Comparison of platelet membrane markers for the detection of platelet activation in vitro and during platelet storage and cardiopulmonary bypass surgery.
Changes in the platelet plasma membrane during activation were investigated by flow cytometry in a comparative study of in vitro… 
Highly Cited
1992
Highly Cited
1992
The cell adhesion molecule CD31 is phosphorylated after cell activation. Down-regulation of CD31 in activated T lymphocytes.
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