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ABSTRACT The antiapoptotic protein PED/PEA-15 features an Akt phosphorylation motif upstream from Ser116. In vitro, recombinant… Expand The ERK 1/2 MAP kinase pathway controls cell growth and survival and modulates integrin function. Here, we report that PEA-15, a… Expand The developmental program of cell-type switching of S. pombe requires a strand-specific imprinting event at the mating-type locus… Expand PED/PEA-15 is a recently cloned 15 kDa protein possessing a death effector domain (DED). In MCF-7 and HeLa cells, a fivefold… Expand The fission yeast Schizosaccharomyces pombe normally has haploid cells of two mating types, which differ at the chromosomal locus… Expand Apoptosis is a very general phenomenon, but only a few reports concern astrocytes. Indeed, astrocytes express receptors for tumor… Expand We have used differential display to identify genes whose expression is altered in type 2 diabetes thus contributing to its… Expand The kinase responsible for Thr161‐Thr160 phosphorylation and activation of cdc2/cdk2 (CAK:cdk‐activating kinase) has been shown… Expand Abstract: PEA‐15 has recently been identified as a major phosphoprotein in astrocytes and an endogenous substrate for protein… Expand Astrocytes in the central nervous system are involved in a variety of functions including storage of glycogen, maintenance of the… Expand