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PDX1 gene

Known as: IDX-1, PANCREAS/DUODENUM HOMEOBOX PROTEIN 1, Pancreatic and Duodenal Homeobox 1 Gene 
This gene plays a role in the regulation of insulin and insulin-responsive genes.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Heterozygous mutations in the gene encoding the pancreatic homeodomain transcription factor pancreatic duodenal homeobox 1 (PDX1… Expand
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Highly Cited
2008
Highly Cited
2008
Intrauterine growth retardation (IUGR) has been linked to the onset of diseases in adulthood, including type 2 diabetes, and has… Expand
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Highly Cited
2008
Highly Cited
2008
The onset of pancreas development in the foregut endoderm is marked by activation of the homeobox gene Pdx1 (IPF1). Pdx1 is… Expand
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Highly Cited
2008
Highly Cited
2008
Despite medical advice, 20-30% of female smokers continue to smoke during pregnancy. Epidemiological studies have associated… Expand
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Highly Cited
2003
Highly Cited
2003
To explore induced islet neogenesis in the liver as a strategy for the treatment of diabetes, we used helper-dependent adenovirus… Expand
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Highly Cited
2002
Highly Cited
2002
The transcription factor Pdx1 is expressed in the pancreatic beta-cell, where it is believed to regulate several beta-cell… Expand
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Highly Cited
1997
Highly Cited
1997
The homeodomain protein IPF1 (also known as IDX1, STF1 and PDX1; see Methods) is critical for development of the pancreas in mice… Expand
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Highly Cited
1996
Highly Cited
1996
It has been proposed that the Xenopus homeobox gene, XlHbox8, is involved in endodermal differentiation during pancreatic and… Expand
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Highly Cited
1994
Highly Cited
1994
THE mammalian pancreas is a mixed exocrine and endocrine gland that, in most species, arises from ventral and dorsal buds which… Expand
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Highly Cited
1993
Highly Cited
1993
We describe the cloning of insulin promoter factor 1 (IPF1), a homeodomain protein which in the adult mouse pancreas is… Expand
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