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PDX1 gene
Known as:
IDX-1
, PANCREAS/DUODENUM HOMEOBOX PROTEIN 1
, Pancreatic and Duodenal Homeobox 1 Gene
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This gene plays a role in the regulation of insulin and insulin-responsive genes.
National Institutes of Health
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Related topics
Related topics
9 relations
Carbohydrate Metabolism
Cell Differentiation process
Homo sapiens
PDX1 protein, human
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization
R. An
,
G. da Silva Xavier
,
+7 authors
G. Rutter
Biochemical and Biophysical Research…
2010
Corpus ID: 10672675
Highly Cited
2008
Highly Cited
2008
Association of genetic variants with atherothrombotic cerebral infarction in Japanese individuals with metabolic syndrome.
Yoshiji Yamada
,
Kimihiko Kato
,
+12 authors
Y. Nozawa
International Journal of Molecular Medicine
2008
Corpus ID: 19687548
Metabolic syndrome is a risk factor for cardiovascular disease. The aim of the present study was to identify genetic variants…
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2007
2007
Activin B mediated induction of Pdx1 in human embryonic stem cell derived embryoid bodies.
U. Frandsen
,
Ann Dorte Pørneki
,
C. Floridon
,
B. Abdallah
,
M. Kassem
Biochemical and Biophysical Research…
2007
Corpus ID: 8683770
Highly Cited
2006
Highly Cited
2006
Assessment of genetic risk for myocardial infarction
Yoshiji Yamada
,
H. Matsuo
,
+9 authors
Y. Nozawa
Thrombosis and Haemostasis
2006
Corpus ID: 46265732
Summary Although lifestyle and environmental factors influence the prevalence of myocardial infarction, genetic epidemiological…
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2006
2006
Stimulation of cAMP signalling allows isolation of clonal pancreatic precursor cells from adult mouse pancreas
T. Yamamoto
,
E. Yamato
,
+6 authors
J. Miyazaki
Diabetologia
2006
Corpus ID: 2108128
Aims/hypothesisDuct cells of the pancreas are thought to include latent progenitors of islet endocrine cells that can be induced…
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2005
2005
The coactivator Bridge-1 increases transcriptional activation by pancreas duodenum homeobox-1 (PDX-1)
V. Stanojevic
,
K. Yao
,
Melissa K Thomas
Molecular and Cellular Endocrinology
2005
Corpus ID: 22465300
Highly Cited
2004
Highly Cited
2004
Identification of PCIF1, a POZ Domain Protein That Inhibits PDX-1 (MODY4) Transcriptional Activity
Aihua Liu
,
B. Desai
,
D. Stoffers
Molecular and Cellular Biology
2004
Corpus ID: 45959356
ABSTRACT Hox factors are evolutionarily conserved homeodomain-containing transcription factors that activate and repress gene…
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Highly Cited
2001
Highly Cited
2001
Functional consequences of mutations in the MODY4 gene (IPF1) and coexistence with MODY3 mutations
J. Weng
,
W. Macfarlane
,
+6 authors
L. Groop
Diabetologia
2001
Corpus ID: 6728416
Aims/hypothesis. The aim of this study was to examine the putative role of mutations in the insulin promoter 1 (IPF1) gene in…
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1998
1998
Misexpression of the pancreatic homeodomain protein IDX-1 by the Hoxa-4 promoter associated with agenesis of the cecum.
R. Heller
,
D. Stoffers
,
M. Hussain
,
C. Miller
,
J. Habener
Gastroenterology
1998
Corpus ID: 45433130
Highly Cited
1996
Highly Cited
1996
Functional regions of the homeodomain protein IDX-1 required for transactivation of the rat somatostatin gene.
M. Lu
,
C. Miller
,
J. Habener
Endocrinology
1996
Corpus ID: 36993516
The insulin-, glucagon- and somatostatin-producing cells (beta, alpha, and delta, respectively) in the pancreatic islets derive…
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