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PDX1 gene

Known as: IDX-1, PANCREAS/DUODENUM HOMEOBOX PROTEIN 1, Pancreatic and Duodenal Homeobox 1 Gene 
This gene plays a role in the regulation of insulin and insulin-responsive genes.
National Institutes of Health

Related topics

Related topics

9 relations
Carbohydrate MetabolismCell Differentiation processHomo sapiensPDX1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Association of genetic variants with atherothrombotic cerebral infarction in Japanese individuals with metabolic syndrome.
Metabolic syndrome is a risk factor for cardiovascular disease. The aim of the present study was to identify genetic variants… 
2008
2008
Coexpression of Pdx1 and betacellulin in mesenchymal stem cells could promote the differentiation of nestin-positive epithelium-like progenitors and pancreatic islet-like spheroids.
Mesenchymal stem cells (MSCs) have already been proved to be multipotent. Our goal was to evaluate the differentiating ability of… 
2007
2007
Activin B mediated induction of Pdx1 in human embryonic stem cell derived embryoid bodies.
Highly Cited
2006
Highly Cited
2006
Assessment of genetic risk for myocardial infarction
Summary Although lifestyle and environmental factors influence the prevalence of myocardial infarction, genetic epidemiological… 
2006
2006
Stimulation of cAMP signalling allows isolation of clonal pancreatic precursor cells from adult mouse pancreas
Aims/hypothesisDuct cells of the pancreas are thought to include latent progenitors of islet endocrine cells that can be induced… 
2005
2005
The coactivator Bridge-1 increases transcriptional activation by pancreas duodenum homeobox-1 (PDX-1)
Highly Cited
2004
Highly Cited
2004
Identification of PCIF1, a POZ Domain Protein That Inhibits PDX-1 (MODY4) Transcriptional Activity
ABSTRACT Hox factors are evolutionarily conserved homeodomain-containing transcription factors that activate and repress gene… 
Highly Cited
2001
Highly Cited
2001
Functional consequences of mutations in the MODY4 gene (IPF1) and coexistence with MODY3 mutations
Aims/hypothesis. The aim of this study was to examine the putative role of mutations in the insulin promoter 1 (IPF1) gene in… 
1998
1998
Misexpression of the pancreatic homeodomain protein IDX-1 by the Hoxa-4 promoter associated with agenesis of the cecum.
1991
1991
Novel insulin promoter- and enhancer-binding proteins that discriminate between pancreatic alpha- and beta-cells.
In the mouse insulin is first detected on embryonic day 12 (e12) in a subpopulation of the cells that on e10 start to produce… 
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