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PDPK1 protein, human

Known as: hPDK1, PDPK1, 3-phosphoinositide dependent protein kinase-1, human 
3-phosphoinositide-dependent protein kinase 1 (556 aa, ~63 kDa) is encoded by the human PDPK1 gene. This protein plays a role in signaling cascade… 
National Institutes of Health

Related topics

Related topics

36 relations

Broader (3)

3-Phosphoinositide Dependent Protein Kinase-13-phosphoinositide-dependent protein kinaseProtein Kinases
AKT Signaling PathwayAngiogenesis PathwayB Cell Receptor Signaling PathwayBeta-Catenin Accumulation Pathway

Papers overview

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2015
2015
Abstract 1754: BPR2P001S0, a Coumarin derivative, induced cell cycle arrest in A549 through inhibiting PDPK1 activity
Lung cancer is one of the most common causes of cancer deaths in the world, and the emergence of resistant lung cancer cells can… 
2015
2015
A Novel Inhibitor of AKT 1 – PDPK 1 Interaction Ef fi ciently Suppresses the Activity of AKT Pathway and Restricts Tumor Growth In Vivo
The serine/threonine kinase AKT/PKB has a critical role in the regulation of cell proliferation. Because AKT signaling is… 
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