3-phosphoinositide-dependent protein kinase

Known as: Protein Kinases, 3-Phosphoinositide-Dependent, 3 Phosphoinositide Dependent Protein Kinase, 3-Phosphoinositide-Dependent Protein Kinases 
Highly conserved protein-serine threonine kinases that phosphorylate and activate a group of AGC protein kinases, especially in response to the… (More)

Topic mentions per year

Topic mentions per year

1997-2018
051019972018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
3-Phosphoinositide-dependent kinase 1 (PDK1) plays a central role in regulating the activity of protein kinases that are… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • table 2
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Protein kinase B (PKB/Akt) is a pivotal regulator of diverse metabolic, phenotypic, and antiapoptotic cellular controls and has… (More)
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2006
2006
Activity of the serine-threonine protein kinase PINOID (PID) has been implicated in the asymmetrical localization of the membrane… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
2005
2005
3-Phosphoinositide-dependent protein kinase 1 (PDK1), a member of the serine/threonine kinase family, has been demonstrated to be… (More)
Is this relevant?
2004
2004
The Saccharomyces cerevisiae homologs, Pkh1/2p, of the mammalian 3-phosphoinositide-dependent protein kinase 1 (PDK1) regulate… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
BACKGROUND Protein kinase B (PKB), and the p70 and p90 ribosomal S6 kinases (p70 S6 kinase and p90 Rsk, respectively), are… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2000
2000
The protein kinase C-related protein kinases (PRKs) have been shown to be under the control of the Rho GTPases and influenced by… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
p70 S6 kinase alpha (p70alpha) is activated in vivo through a multisite phosphorylation in response to mitogens if a sufficient… (More)
Is this relevant?
1999
1999
Protein kinase B (PKB or Akt), a downstream effector of phosphoinositide 3-kinase (PI 3-kinase), has been implicated in insulin… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
BACKGROUND The p70 S6 kinase, an enzyme critical for cell-cycle progression through the G1 phase, is activated in vivo by insulin… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?