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PDE10A gene

Known as: PDE10A, PHOSPHODIESTERASE 10A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Pharmacological Phosphodiesterase Inhibition as a Therapeutic for Cortical and Striatal Stroke
Author(s): Abduljawad, Nora | Advisor(s): Carmichael, S. Thomas | Abstract: Stroke is the leading cause of adult disability, but… 
2018
2018
Characterisation of PDE10A degradation and disease-associated mutations
2017
2017
Loss of PDE10A expression in patients with PDE10A and ADYC5 mutations
2017
2017
Inhibitors of cGMP 3’,5’-Cyclic Phosphodiesterase 10A: A QSAR Study
A series of compounds with known experimental IC50 (nM) targeting phosphodiesterase10A (PDE10A) was studied. Recently PDE10A was… 
2014
2014
In vivo visualization of PDE10A using positron emission tomography
2013
2013
Dérivés de 6,7-dialcoxy-3-isoquinoline substitués à titre d'inhibiteurs de phosphodiestérase 10 (pde10a)
Cette invention concerne des composes de formule (I) ou un sel pharmaceutiquement acceptable de ceux-ci - R', R 1 a R 7 et Ar… 
2013
2013
The novel inhibitor compounds of phosphodiesterase 10a-type
The present invention provides compounds of formula I, these N- oxides, tautomers, relates acceptable salts prodrugs and… 
2012
2012
Whole-body biodistribution and dosimetry of 18F-JNJ42259152: A novel radioligand for human in vivo PDE10A brain imaging
2012
2012
Dérivés de 6,7-dialkoxy-3-isoquinolinol substitués en tant qu'inhibiteurs de la phosphodiestérase 10 (pde10a)
La presente invention concerne des composes de la formule indiquee ici, R', R 1 a R 7 et Ar etant tels que definis ici. Lesdits… 
2010
2010
2-arylimidazolderivater as pde10a-enzyme inhibitors