PDE10A gene

Known as: PDE10A, PHOSPHODIESTERASE 10A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
0204019992017

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND Huntington's disease is a devastating neurodegenerative condition for which there is no therapy to slow disease… (More)
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Highly Cited
2008
Highly Cited
2008
Phosphodiesterase (PDE) is a critical regulator of cAMP/protein kinase A (PKA) signaling in cells. Multiple PDEs with different… (More)
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Highly Cited
2006
Highly Cited
2006
Phosphodiesterase 10A (PDE10A) is a recently identified cyclic nucleotide phosphodiesterase expressed primarily in… (More)
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Highly Cited
2006
Highly Cited
2006
PDE10A is a recently identified phosphodiesterase that is highly expressed by the GABAergic medium spiny projection neurons of… (More)
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Highly Cited
2006
Highly Cited
2006
PDE10A is a newly identified phosphodiesterase that is highly expressed by the medium spiny projection neurons of the striatum… (More)
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Highly Cited
2005
Highly Cited
2005
Persistent suppression of N-methyl-d-aspartate (NMDA) receptor function produces enduring structural changes in neocortical and… (More)
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Highly Cited
2003
Highly Cited
2003
PDE10A is a newly identified cAMP/cGMP phosphodiesterase for which mRNA is highly expressed in the mammalian striatum. In the… (More)
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Highly Cited
1999
Highly Cited
1999
cDNA encoding a novel phosphodiesterase (PDE) was isolated from a human fetal lung cDNA library and designated PDE10A. The… (More)
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1999
1999
PDE10A, a phosphodiesterase (PDE) exhibiting properties of a cAMP PDE and a cAMP-inhibited cGMP PDE, was cloned and investigated… (More)
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Highly Cited
1999
Highly Cited
1999
A gene encoding a novel human 3', 5'-cyclic nucleotide phosphodiesterase (PDE) was identified and characterized. PDE10A1 encodes… (More)
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