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PDC gene

Known as: PHOSDUCIN, MEKA, PDC 
This gene plays a role in cell signaling and the regulation of phototransduction.
National Institutes of Health

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PDC wt Allele
PDC, veterinary productSignal TransductionVisual Perceptionphosducin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Splice Isoforms of Phosducin-like Protein Control the Expression of Heterotrimeric G Proteins*
Background: Heterotrimeric G proteins are essential for biological signaling; however, the mechanism of their biosynthesis… 
2005
2005
The phosducin-like protein PhLP1 is essential for G{beta}{gamma} dimer formation in Dictyostelium discoideum.
Phosducin proteins are known to inhibit G protein-mediated signaling by sequestering Gbetagamma subunits. However, Dictyostelium… 
2003
2003
Effects of two Gbetagamma-binding proteins--N-terminally truncated phosducin and beta-adrenergic receptor kinase C terminus (betaARKct)--in heart failure.
Myocardial overexpression of the C-terminus of beta-adrenergic receptor kinase (betaARKct) has been shown to result in a positive… 
2003
2003
A Novel Germ Line-specific Gene of the Phosducin-like Protein (PhLP) Family
We identified a new member of the phosducin-like (PhLP) protein family that is predominantly, if not exclusively, expressed in… 
1997
1997
PhLPs and PhLOPs in the phosducin family of Gβγ binding proteins
In this study, we identify new isoforms of the retinal phosducin and investigate the expression of the phosducin family, showing… 
1997
1997
Characterization of a potent uveitopathogenic site derived from rat phosducin.
Phosducin is a retinal and pineal phosphoprotein assumed to play an important role in visual phototransduction. Phosducin is also… 
1994
1994
The sequence of the human phosducin gene (PDC) and its 5'-flanking region.
Phosducin, a principal protein of the retinal photoreceptor cells, modulates the phototransduction cascade by interacting with… 
1993
1993
Identification of cyclic nucleotide-regulated phosphoproteins, including phosducin, in motile rod inner-outer segments of teleosts.
In teleost retinas, rods elongate in the light and shorten in the dark. Rod motility is mediated by the actin cytoskeleton of the… 
1991
1991
Photoneural control of the synthesis and phosphorylation of pineal MEKA (phosducin).
MEKA is an acidic 33-kilodalton phosphoprotein found in the retina and pineal gland. It is of interest because it forms a… 
Highly Cited
1990
Highly Cited
1990
Amino acid and cDNA sequence of bovine phosducin, a soluble phosphoprotein from photoreceptor cells.
Vertebrate photoreceptor cells contain a soluble phosphoprotein, phosducin, which complexes with the beta, gamma subunits of the… 
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