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PDC gene

Known as: PHOSDUCIN, MEKA, PDC 
This gene plays a role in cell signaling and the regulation of phototransduction.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
Members of the phosducin gene family were initially proposed to act as down-regulators of G protein signaling by binding G… Expand
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Highly Cited
2004
Highly Cited
2004
PURPOSE To examine an immortalized mouse retinal cell line (661W) for markers characteristic of photoreceptor cells and validate… Expand
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Highly Cited
2004
Highly Cited
2004
Phosducin is a photoreceptor-specific protein known to interact with the βγ subunits of G proteins. In pursuit of the function of… Expand
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Highly Cited
2002
Highly Cited
2002
While the pathologic mechanisms responsible for organ-specific tissue damage in primary biliary cirrhosis (PBC) remain an enigma… Expand
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Highly Cited
1999
Highly Cited
1999
Mutations in rod opsin, the visual pigment protein of rod photoreceptors, account for approximately 15% of all inherited human… Expand
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Highly Cited
1999
Highly Cited
1999
Homologous desensitization of G protein-coupled receptors is thought to occur in several steps: binding of G protein-coupled… Expand
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Highly Cited
1996
Highly Cited
1996
Abstract The crystal structure of transducin's βγ subunits complexed with phosducin, which regulates G t βγ activity, has been… Expand
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Highly Cited
1994
Highly Cited
1994
Heterotrimeric GTP-binding proteins (G-proteins) serve many different signal transduction pathways. Phosducin, a 28-kDa… Expand
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Highly Cited
1992
Highly Cited
1992
SIGNAL transduction by G-protein-coupled receptors is regulated by various mechanisms acting at the receptor level; those studied… Expand
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Highly Cited
1992
Highly Cited
1992
Photoexcitation of retinal rod photoreceptor cells involves the activation of cGMP enzyme cascade in which sequential activation… Expand
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