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Targeted disruption of a fungal G-protein beta subunit gene results in increased vegetative growth but reduced virulence.
TLDR
Results obtained for Gi alpha gene disruption revealed roles for the Gi alpha subunit CPG-1 in fungal reproduction, virulence, and vegetative growth, and the reduction in virulence resulting from the disruption of a G beta gene was accompanied by increased, rather than decreased, Vegetative growth on synthetic medium.
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Identification of bdm-1, a gene involved in G protein β-subunit function and α-subunit accumulation
TLDR
The genetic data presented in this report suggest that BDM-1 is required for or facilitates Gbeta function, a key Galpha subunit required for a range of vital physiological processes.
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Cloning of the Saccharomyces cerevisiae gene whose overexpression overcomes the effects of HM-1 killer toxin, which inhibits beta-glucan synthesis
TLDR
Overexpression of the truncated HKR1 encoding the C-terminal half of Hkr1p made the cells more resistant to HM-1 killer toxin than the full-length H KR1 did, demonstrating that the C -terminalhalf of HKR 1p is essential for overcoming the effect of HM- 1 killer toxin.
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An ordered collection of expressed sequences from Cryphonectria parasitica and evidence of genomic microsynteny with Neurospora crassa and Magnaporthe grisea.
TLDR
These data represent the largest collection of sequence information currently available for C. parasitica and are now forming the basis of further studies using microarray analyses to determine global changes in transcription that occur in response to hypovirus infection.
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HKR1 encodes a cell surface protein that regulates both cell wall beta-glucan synthesis and budding pattern in the yeast Saccharomyces cerevisiae
TLDR
Results demonstrate that HKR1 encodes a cell surface protein that regulates both cell wall beta-glucan synthesis and budding pattern and suggest that bud site assembly is somehow related to beta- glucan synthesisation in S. cerevisiae.
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Cloning and Expression of the Exo-β-D-1,3-glucanase Gene (exgS) from Aspergillus saitoi
TLDR
The deduced amino acid sequences showed that the ExgS has a non-homologous linker region consisting of 180 amino acids, which encompassed highly conserved regions observed in Exg homologues from filamentous fungi.
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Functional Analysis of the α-1,3-Glucan Synthase Genes agsA and agsB in Aspergillus nidulans: AgsB Is the Major α-1,3-Glucan Synthase in This Fungus
TLDR
It is demonstrated that the two AGS genes are dispensable in A. nidulans, but that AgsB is required for normal growth characteristics under liquid culture conditions and is the major AGS in this species.
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Identification of bdm-1, a gene involved in G protein beta-subunit function and alpha-subunit accumulation.
TLDR
The genetic data presented in this report suggest that BDM-1 is required for or facilitates Gbeta function, a key Galpha subunit required for a range of vital physiological processes.
View on PubMed
The chestnut blight fungus for studies on virus/host and virus/virus interactions: from a natural to a model host.
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Involvement of cell wall β‐glucan in the action of HM‐1 killer toxin
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