PD 173955

Known as: PD-173955, PD173955 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
012319992017

Papers overview

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2017
2017
The receptor tyrosine kinase EPHA2 has gained attention as a therapeutic drug target for cancer and infectious diseases. However… (More)
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2010
2010
The effects of substituents on the aryl ring were studied by the preparation and testing of several PD173955 analogs. Inserting a… (More)
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2008
2008
Protein associations are poorly understood from a chemical perspective. If the contrary were true, drug inhibitors would be… (More)
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2006
2006
Organic small molecules generally act by perturbing the function of one or more cellular target proteins, the identification of… (More)
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2006
2006
Anaplastic lymphoma kinase (ALK) is a valid target for anticancer therapy; however, potent ALK inhibitors suitable for clinical… (More)
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2006
2006
Cerebellar granule neurons undergo apoptosis when switched from culture medium containing depolarizing levels of potassium (high… (More)
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Highly Cited
2002
Highly Cited
2002
The inadvertent fusion of the bcr gene with the abl gene results in a constitutively active tyrosine kinase (Bcr-Abl) that… (More)
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Highly Cited
2002
Highly Cited
2002
The early stage of chronic myelogenous leukemia (CML) is caused by the tyrosine kinase Bcr-Abl. Imatinib mesylate (also known as… (More)
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2002
2002
The early stage of chronic myelogenous leukemia (CML) is caused by the tyrosine kinase Bcr-Abl. Imatinib mesylate (also known as… (More)
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1999
1999
src kinase activity is elevated in some human tumors, including breast and colon cancers. The precise cellular function of the… (More)
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