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PD 169316
Known as:
4-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)-1H-imidazole
, PD-169316
, PD169316
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Enzyme Inhibitors
Imidazoles
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Induction of cardiac fibroblast lysyl oxidase by TGF-β1 requires PI3K/Akt, Smad3, and MAPK signaling.
T. Voloshenyuk
,
Elizabeth S Landesman
,
E. Khoutorova
,
Andrew D Hart
,
J. Gardner
Cytokine
2011
Corpus ID: 25211021
Highly Cited
2008
Highly Cited
2008
The role of p38 MAPK and JNK in Arsenic trioxide‐induced mitochondrial cell death in human cervical cancer cells
Young‐Hee Kang
,
Su-Jae Lee
Journal of Cellular Physiology
2008
Corpus ID: 25492988
Previously, we have shown that the release of AIF from mitochondria is required for As2O3‐induced cell death in human cervical…
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Highly Cited
2006
Highly Cited
2006
Inhibition of p38MAPK increases adipogenesis from embryonic to adult stages.
M. Aouadi
,
K. Laurent
,
M. Prot
,
Y. Le Marchand-Brustel
,
B. Binétruy
,
F. Bost
Diabetes
2006
Corpus ID: 26797945
Formation of new adipocytes from precursor cells contributes to adipose tissue expansion and obesity. In this study, we asked…
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Highly Cited
2005
Highly Cited
2005
A Role for p38 Mitogen-Activated Protein Kinase in the Regulation of the Serotonin Transporter: Evidence for Distinct Cellular Mechanisms Involved in Transporter Surface Expression
D. Samuvel
,
L. D. Jayanthi
,
N. Bhat
,
S. Ramamoorthy
Journal of Neuroscience
2005
Corpus ID: 16511917
The serotonin transporter (SERT) is regulated by various signaling mechanisms that may operate to maintain appropriate levels of…
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Highly Cited
2004
Highly Cited
2004
Phosphorylation of p38 MAPK Induced by Oxidative Stress Is Linked to Activation of Both Caspase-8- and -9-mediated Apoptotic Pathways in Dopaminergic Neurons*
W. Choi
,
D. Eom
,
+7 authors
Y. Oh
Journal of Biological Chemistry
2004
Corpus ID: 26664532
We evaluated the contribution of p38 mitogen-activated protein kinase and the events upstream/downstream of p38 leading to…
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Highly Cited
2002
Highly Cited
2002
Biologic sequelae of nuclear factor-kappaB blockade in multiple myeloma: therapeutic applications.
N. Mitsiades
,
C. Mitsiades
,
+6 authors
K. Anderson
Blood
2002
Corpus ID: 3094507
The transcription factor nuclear factor-kappaB (NF-kappaB) confers significant survival potential in a variety of tumors. Several…
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Highly Cited
2002
Highly Cited
2002
ATM Mediates Phosphorylation at Multiple p53 Sites, Including Ser46, in Response to Ionizing Radiation*
Shinichi Saito
,
A. A. Goodarzi
,
+4 authors
C. Anderson
Journal of Biological Chemistry
2002
Corpus ID: 21987313
The p53 tumor suppressor protein preserves genome integrity by regulating growth arrest and apoptosis in response to DNA damage…
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Highly Cited
2001
Highly Cited
2001
Insulin signaling leading to proliferation, survival, and membrane ruffling in C2C12 myoblasts
R. Conejo
,
M. Lorenzo
Journal of Cellular Physiology
2001
Corpus ID: 21226576
We have recently shown that insulin induced myogenesis in the mouse C2C12 skeletal muscle cell line by activation of…
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Highly Cited
1999
Highly Cited
1999
The Activation of the c-Jun N-terminal Kinase and p38 Mitogen-activated Protein Kinase Signaling Pathways Protects HeLa Cells from Apoptosis Following Photodynamic Therapy with Hypericin*
Z. Assefa
,
A. Vantieghem
,
+5 authors
P. Agostinis
Journal of Biological Chemistry
1999
Corpus ID: 26030039
In this study, we elucidate signaling pathways induced by photodynamic therapy (PDT) with hypericin. We show that PDT rapidly…
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Highly Cited
1997
Highly Cited
1997
Apoptosis Induced by Withdrawal of Trophic Factors Is Mediated by p38 Mitogen-activated Protein Kinase*
Jennifer L. Kummer
,
Pravin K. Rao
,
K. Heidenreich
Journal of Biological Chemistry
1997
Corpus ID: 22899565
p38 is a member of the mitogen-activated protein (MAP) kinase superfamily activated by stress signals and implicated in cellular…
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