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PD-117596

Known as: PD 117596 
National Institutes of Health

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Fluoroquinolones

Papers overview

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2000
2000
Evaluation of toxicokinetic variables and arthropathic changes in juvenile rabbits after oral administration of an investigational fluoroquinolone, PD 117596.
OBJECTIVE To compare toxicokinetic variables and associated tissue drug concentrations with severity of articular lesions in… 
1999
1999
In vitro activity of eight fluoroquinolones against multiresistant Stenotrophomonas maltophilia.
We studied the activity of eight fluoroquinolones (norfloxacin, ciprofloxacin, grepafloxacin, trovafloxacin, gatifloxacin… 
1996
1996
Quinolone arthropathy in immature rabbits treated with the fluoroquinolone, PD 117596.
1995
1995
Susceptibilities of Brucella melitensis isolates to clinafloxacin and four other new fluoroquinolones
The susceptibilities of 120 clinical isolates of Brucella melitensis and 3 reference strains of the same species to six… 
Highly Cited
1991
Highly Cited
1991
Mechanistic studies of the phototoxic potential of PD 117596, a quinolone antibacterial compound.
1991
1991
Phenotypic characterization of quinolone-resistant mutants of Enterobacteriaceae selected from wild type, gyrA type and multiply-resistant (marA) type strains.
The NCTC type strains of Escherichia coli, Enterobacter cloacae, Serratia marcescens and Klebsiella pneumoniae were exposed to 3… 
1991
1991
Anti-Mycobacterium leprae activity of several quinolones studied in the mouse.
The anti-Mycobacterium leprae activity of several fluoroquinolones (A-56619, A-56620, ofloxacin, fleroxacin, lomefloxacin… 
Highly Cited
1990
Highly Cited
1990
Comparative in vitro activities of 20 fluoroquinolones against Mycobacterium leprae
The in vitro activities of 20 fluoroquinolones against Mycobacterium leprae were evaluated by using the BACTEC 460 system. M… 
1989
1989
In vitro activity of PD 117596-2, a broad-spectrum difluoroquinolone
The activity of PD 117596-2, a novel quinolone, was compared to that of other quinolones, ceftazidime, imipenem and gentamicin… 
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