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PCSK9 gene
Known as:
NARC-1
, NEURAL APOPTOSIS-REGULATED CONVERTASE 1
, Proprotein Convertase Subtilisin/Kexin Type 9 Gene
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This gene is involved in both cholesterol metabolism and protein degradation.
National Institutes of Health
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Related topics
Related topics
7 relations
Cholesterol Homeostasis
HYPERCHOLESTEROLEMIA, AUTOSOMAL DOMINANT, 3
Hydrolysis
PCSK9 protein, human
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Circulating Rather Than Intestinal PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Regulates Postprandial Lipemia in Mice
D. Garçon
,
F. Moreau
,
+8 authors
C. Le May
Arteriosclerosis, Thrombosis and Vascular Biology
2020
Corpus ID: 220608802
Supplemental Digital Content is available in the text. Objective: Increased postprandial lipemia (PPL) is an independent risk…
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2015
2015
Diabetes with poor glycaemic control does not promote atherosclerosis in genetically modified hypercholesterolaemic minipigs
Rozh H. Al-Mashhadi
,
M. M. Bjørklund
,
+4 authors
J. Bentzon
Diabetologia
2015
Corpus ID: 12831169
Aims/hypothesisDiabetes is associated with an increased risk of atherosclerotic cardiovascular disease, but whether there is a…
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Review
2015
Review
2015
PCSK9 and triglyceride-rich lipoprotein metabolism
Irena Druce
,
Hussein Abujrad
,
T. Ooi
Journal of Biomedical Research
2015
Corpus ID: 19311824
Abstract Pro-protein convertase subtilisin-kexin 9 (PCSK9) is known to affect low-density lipoprotein (LDL) metabolism, but there…
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2014
2014
Influence of PCSK9 polymorphisms on plasma lipids and response to atorvastatin treatment in Brazilian subjects.
J. Anderson
,
Álvaro Cerda
,
+6 authors
R. Hirata
Journal of Clinical Lipidology
2014
Corpus ID: 24495692
2013
2013
Mutation in the PCSK9 Gene in Omani Arab Subjects with Autosomal Dominant Hypercholesterolemia and its Effect on PCSK9 Protein Structure.
K. Al-Waili
,
Ward Al-Muna Al-Zidi
,
+6 authors
Yajnavalka Banerjee
Oman Medical Journal
2013
Corpus ID: 22215530
Proprotein convertase subtilisin/kexin type (PCSK9) is a crucial protein in LDL cholesterol (LDL-C) metabolism by virtue of its…
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2012
2012
Genetic variation in APOB, PCSK9, and ANGPTL3 in carriers of pathogenic autosomal dominant hypercholesterolemic mutations with unexpected low LDL‐Cl Levels
R. Huijgen
,
B. Sjouke
,
+5 authors
S. Fouchier
Human Mutation
2012
Corpus ID: 1182077
Autosomal Dominant Hypercholesterolemia (ADH) is caused by LDLR and APOB mutations. However, genetically diagnosed ADH patients…
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2008
2008
A PCSK9 variant and familial combined hyperlipidaemia
M. Abifadel
,
L. Bernier
,
+12 authors
C. Boileau
Journal of Medical Genetics
2008
Corpus ID: 20022571
Background: Our discovery in 2003 of the first mutations of PCSK9 gene causing autosomal dominant hypercholesterolaemia (ADH…
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Review
2008
Review
2008
Further LDL cholesterol lowering through targeting PCSK9 for coronary artery disease.
Guoqing Cao
,
Y. Qian
,
M. Kowala
,
R. Konrad
Endocrine, Metabolic & Immune Disorders - Drug…
2008
Corpus ID: 23939302
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease that belongs to the proprotein convertase family…
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Highly Cited
2004
Highly Cited
2004
Genetic variants in PCSK9 affect the cholesterol level in Japanese
K. Shioji
,
T. Mannami
,
+5 authors
N. Iwai
Journal of Human Genetics
2004
Corpus ID: 24107691
AbstractMutations in the proprotein convertase subtilisin/kexin 9 (PCSK9) gene have been reported in affected members of two…
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1989
1989
FH3, a v-myc avian retrovirus with limited transforming ability
C. Chen
,
B. Biegalke
,
R. Eisenman
,
M. Linial
Journal of Virology
1989
Corpus ID: 33105761
We have isolated a new acute avian transforming virus which contains the oncogene myc. This virus, designated FH3, was isolated…
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