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PCSK1 gene

Known as: PC3, NEC1, PCSK1 
This gene plays a role in the metabolism of prohormones and neuropeptides.
National Institutes of Health

Related topics

Related topics

10 relations
HydrolysisPCSK1 protein, humanPCSK1 wt AllelePCSK2 gene

Papers overview

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Highly Cited
2012
Highly Cited
2012
Common Variants in FTO, MC4R, TMEM18, PRL, AIF1, and PCSK1 Show Evidence of Association With Adult Obesity in the Greek Population
Twenty‐four single‐nucleotide polymorphisms (SNPs) have been reproducibly associated with obesity. We performed a follow‐up study… 
Highly Cited
2009
Highly Cited
2009
SCG3 Transcript in Peripheral Blood Is a Prognostic Biomarker for REST-Deficient Small Cell Lung Cancer
Purpose: Specific markers of circulating tumor cells may be informative in managing lung cancer. Because the RE-1 silencing… 
2005
2005
Cholecystokinin Levels in Prohormone Convertase 2 Knock-out Mouse Brain Regions Reveal a Complex Phenotype of Region-specific Alterations*
Prohormone convertase 2 is widely co-localized with cholecystokinin in rodent brain. To examine its role in cholecystokinin… 
1997
1997
Prohormone Convertase 1 Is Necessary for the Formation of Cholecystokinin 8 in Rin5F and STC-1 Cells*
Several immortalized cell lines serve as models for procholecystokinin (pro-CCK) processing. Rin5F cells, derived from a rat… 
Highly Cited
1996
Highly Cited
1996
SPC3, a V3 loop-derived synthetic peptide inhibitor of HIV-1 infection, binds to cell surface glycosphingolipids.
Synthetic multibranched peptides derived from the V3 domain of human immunodeficiency virus type 1 (HIV-1) gp120 inhibit HIV-1… 
1995
1995
Mutational Analysis of PC1 (SPC3) in PC12 Cells
The proteinase mPC1, a neuroendocrine member of the mammalian family of subtilisin-like enzymes, has previously been shown to be… 
1995
1995
Molecular Modeling of the Substrate Specificity of Prohormone Convertases SPC2 and SPC3 (*)
In this paper we describe the results of molecular modeling of the structures of the active sites of two subtilisin-like… 
1994
1994
In vitro processing of proopiomelanocortin by recombinant PC1 (SPC3).
The prohormone convertases, PC1 (SPC3) and PC2, are subtilisin-like serine proteases capable of processing neuropeptide… 
1994
1994
Distribution and regulation of the candidate prohormone processing enzymes SPC2 and SPC3 in adult rat brain
1993
1993
Purification and characterization of the candidate prohormone-processing enzyme SPC3 produced in a mouse L cell line.
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