PCSK1 gene

Known as: PC3, NEC1, PCSK1 
This gene plays a role in the metabolism of prohormones and neuropeptides.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1988-2017
05101519882017

Papers overview

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2012
2012
Twenty-four single-nucleotide polymorphisms (SNPs) have been reproducibly associated with obesity. We performed a follow-up study… (More)
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Highly Cited
2012
Highly Cited
2012
Multiple genetic loci associated with obesity or body mass index (BMI) have been identified through genome-wide association… (More)
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2011
2011
TCF7L2 and SLC30A8 have been found to be associated with type 2 diabetes mellitus (T2DM) as well as with impaired proinsulin… (More)
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2010
2010
BACKGROUND Common variants in PCSK1 have been reported to be associated with obesity in populations of European origin. We aimed… (More)
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2010
2010
Prohormone convertase 1 is involved in maturation of peptides. Rare mutations in gene PCSK1, encoding this enzyme, cause… (More)
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2010
2010
Proprotein convertase 1 (PCSK1) is an endopeptidase involved in proteolytic processing of peptide hormone precursors in granules… (More)
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2010
2010
Prohormone convertase subtilisin/kexin type 1 (PCSK1) genetic polymorphisms have recently been associated with obesity in… (More)
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2009
2009
Recently, the rs6232 (N221D) and rs6235 (S690T) SNPs in the PCSK1 gene were associated with obesity in a meta-analysis comprising… (More)
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Highly Cited
2008
Highly Cited
2008
Mutations in PCSK1 cause monogenic obesity. To assess the contribution of PCSK1 to polygenic obesity risk, we genotyped tag SNPs… (More)
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2008
2008
Alveolar soft-part sarcoma (ASPS) is an extremely rare, highly vascular soft tissue sarcoma affecting predominantly adolescents… (More)
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