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PC12 Cells

Known as: PC12 Cell, Pheochromocytoma 12 Cell Line, Cell Line, Pheochromocytoma 
A CELL LINE derived from a PHEOCHROMOCYTOMA of the rat ADRENAL MEDULLA. PC12 cells stop dividing and undergo terminal differentiation when treated… 
National Institutes of Health

Related topics

Related topics

8 relations

Broader (3)

Clone CellsCultured Cell LineNeoplastic Cell
HybridomasMicrobiologicalProcess of secretionaspects of radiation effects

Papers overview

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Highly Cited
1994
Highly Cited
1994
Growth factors differentially stimulate the phosphorylation of Shc proteins and their association with Grb2 in PC-12 pheochromocytoma cells.
Highly Cited
1990
Highly Cited
1990
Differential effects of NGF, FGF, EGF, cAMP, and dexamethasone on neurite outgrowth and sodium channel expression in PC12 cells
PC12 cells are a pheochromocytoma cell line that can be made to differentiate into sympatheticlike neurons by nerve growth factor… 
Highly Cited
1990
Highly Cited
1990
A biological role of the carbohydrate moieties of laminin.
Highly Cited
1990
Highly Cited
1990
Adrenal pheochromocytoma PC12h cells respond to pituitary adenylate cyclase activating polypeptide.
Highly Cited
1989
Highly Cited
1989
Nerve growth factor stimulates the hydrolysis of glycosylphosphatidylinositol in PC-12 cells: a mechanism of protein kinase C regulation.
Treatment of PC-12 pheochromocytoma cells with nerve growth factor (NGF) results in the differentiation of these cells into a… 
Highly Cited
1986
Highly Cited
1986
Nerve growth factor modulates the drug sensitivity of neurotransmitter release from PC-12 cells.
The release of catecholamines from adrenal chromaffin cells is known to be blocked by dihydropyridines, such as nitrendipine, and… 
Highly Cited
1983
Highly Cited
1983
Identification of a Ca2+ requirement for protein synthesis in eukaryotic cells.
Highly Cited
1982
Highly Cited
1982
Neurite outgrowth and protein synthesis by PC12 cells as a function of substratum and nerve growth factor
Numerous studies have implied that enhanced cell-substratum adhesion plays a role in neurite outgrowth by neuronal cells. Using… 
Highly Cited
1981
Highly Cited
1981
Nerve growth factor-mediated stimulation of tyrosine hydroxylase activity in a clonal rat pheochromocytoma cell line
Highly Cited
1979
Highly Cited
1979
Rapid, sequential changes in surface morphology of PC12 pheochromocytoma cells in response to nerve growth factor
The effect of nerve growth factor (NGF), a substance that promotes the differentiation and maintenance of certain neurons, was… 
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