PC12 Cells

Known as: Pheochromocytoma 12 Cell Line, PC12 cell, Cell Line, Pheochromocytoma 
A CELL LINE derived from a PHEOCHROMOCYTOMA of the rat ADRENAL MEDULLA. PC12 cells stop dividing and undergo terminal differentiation when treated… (More)

Topic mentions per year

Topic mentions per year

1975-2017
010020019752017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Alpha-synuclein (alpha-syn), a protein implicated in Parkinson's disease pathogenesis, is a presynaptic protein suggested to… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
We developed a genetically encoded, highly specific fluorescent probe for detecting hydrogen peroxide (H2O2) inside living cells… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Protein conformational disorders (PCDs), such as Alzheimer's disease, Huntington's disease (HD), Parkinson's disease and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Alpha-synuclein mutations have been identified in certain families with Parkinson's disease (PD), and alpha-synuclein is a major… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 6
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Nerve growth factor (NGF) induces both differentiation and survival of neurons by binding to the Trk receptor protein tyrosine… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
The mitogen-activated protein kinase (MAP kinase) pathway is thought to play an important role in the actions of neurotrophins. A… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
The MAP kinase pathway is activated by a wide variety of external signals leading to cell proliferation or differentiation… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
The two forms of pituitary adenylyl cyclase-activating polypeptide (PACAP-27 and -38) are neuropeptides of the secretin/glucagon… (More)
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Expression of oncogenic ras in PC12 cells causes neuronal differentiation and sustained protein tyrosine phosphorylation and… (More)
Is this relevant?
Highly Cited
1976
Highly Cited
1976
A single cell clonal line which responds reversibly to nerve growth factor (NGF) has been established from a transplantable rat… (More)
Is this relevant?