PC-3 cell line

Known as: PC-3 
An adenocarcinoma cell line established in 1979 from a bone metastasis from a 62 year old Caucasian male patient with stage IV prostate carcinoma.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2017
0204019792017

Papers overview

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2012
2012
Emerging evidence demonstrates that cancer stem cells (CSCs) are the critical drivers of tumor progression and metastasis. The… (More)
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2011
2011
INTRODUCTION Honey is a common household product with many medicinal uses described in traditional medicine. Only recently has… (More)
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2007
2007
Icariin and icaritin with prenyl group have been demonstrated for their selective estrogen receptor modulating activities. We… (More)
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Highly Cited
2006
Highly Cited
2006
Berberine, a naturally occurring isoquinoline alkaloid, has been shown to possess anti-inflammatory and antitumor properties in… (More)
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2006
Highly Cited
2006
The development of metastases is a decisive step in the course of a cancer disease. The detection of metastases in cancer… (More)
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2006
Highly Cited
2006
The phosphatidylinositol 3-kinase/Akt pathway plays a critical role in oncogenesis, and dysregulation of this pathway through… (More)
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2004
2004
MAL, BENE and MAL2 are raft-associated integral membrane proteins of the MAL family of proteins involved in membrane trafficking… (More)
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Highly Cited
2002
Highly Cited
2002
Breast and prostate cancer preferentially metastasize in the skeleton, inducing locally increased bone resorption by osteoclasts… (More)
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Highly Cited
2001
Highly Cited
2001
The phosphatidylinositol 3-kinase (PI3K) signaling pathway has inherent oncogenic potential. It is up-regulated in diverse human… (More)
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Highly Cited
1979
Highly Cited
1979
The establishment, characterization, and tumorigenicity of a new epithelial cell line (PC-3) from a human prostatic… (More)
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