PARK7 wt Allele

Known as: DJ1, Parkinson Disease (Autosomal Recessive, Early Oonset) 7 Gene, CTA-215D11.1 
Human PARK7 wild-type allele is located in the vicinity of 1p36.23 and is approximately 31 kb in length. This allele, which encodes protein DJ-1, is… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Mutations in DJ-1, PINK1 (PTEN-induced putative kinase 1) and parkin all cause recessive parkinsonism in humans, but the… (More)
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Highly Cited
2010
Highly Cited
2010
Biomarkers are urgently needed for the diagnosis and monitoring of disease progression in Parkinson's disease. Both DJ-1 and… (More)
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Highly Cited
2008
Highly Cited
2008
RATIONALE Oxidative stress is a key contributor in chronic obstructive pulmonary disease (COPD) pathogenesis caused by cigarette… (More)
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Highly Cited
2006
Highly Cited
2006
DJ-1/PARK7, a cancer- and Parkinson's disease (PD)-associated protein, protects cells from toxic stresses. However, the… (More)
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Highly Cited
2006
Highly Cited
2006
Mutations in DJ-1 cause an autosomal recessive, early onset familial form of Parkinson disease (PD). However, little is presently… (More)
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Highly Cited
2005
Highly Cited
2005
The phosphatidylinositol 3' kinase (PI3'K) pathway, which regulates cell survival, is antagonized by the PTEN tumor suppressor… (More)
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Highly Cited
2005
Highly Cited
2005
DJ-1 is the third gene that has been linked to Parkinson disease. Mutations in the DJ-1 gene cause early onset PD with autosomal… (More)
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Highly Cited
2004
Highly Cited
2004
Parkinson's disease (PD) pathology is characterized by the degeneration of midbrain dopamine neurons (DNs) ultimately leading to… (More)
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Highly Cited
2001
Highly Cited
2001
DJ-1 was first identified as a novel candidate of the oncogene product that transformed mouse NIH3T3 cells in cooperation with an… (More)
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Highly Cited
1997
Highly Cited
1997
We have isolated and characterized the cDNA encoding a novel protein designated DJ-1. DJ-1, sharing no significant homology with… (More)
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