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PARK2 gene

Known as: AR-JP, Parkinson Disease (Autosomal Recessive, Juvenile) 2, Parkin Gene, PRKN 
This gene may play a role in the mediation of proteasomal targeting.
National Institutes of Health

Related topics

Related topics

9 relations
Cell DeathPARK2 protein, humanPARK3 genePARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE

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PARK2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
A Clinicopathologic Entity
Results: Presenting signs in the parkin disease cases were hand or leg tremor often combined with dystonia. Mean age at onset was… 
Review
2013
Review
2013
Variability in clinical phenotypes of heterozygous and homozygous cases of Parkin-related Parkinson's disease
Parkin mutations are a common cause of early-onset Parkinson's disease. To study the clinical features and treatment responses of… 
2011
2011
PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy
2011
2011
Parkin Reduces Expression of Monocyte Chemotactic Protein-1 (MCP-1) in TNF-α-stimulated MCF7 Breast Cancer Cells
Parkin is a putative tumor suppressor protein and its expression is frequently reduced or absent in several types of tumors. In… 
2010
2010
Challenges and Accomplishments: A Celebration of the Arctic Institute of North America
IN THE 1930S, EXPLORER VILHJALMUR STEFANSSON, northern scientists (particularly geologists), and developers such as Gilbert… 
2009
2009
New challenges for informed consent through whole genome array testing
We read with great interest the article by Schwarzbraun et al on predictive diagnosis of Li–Fraumeni syndrome established as an… 
2004
2004
14-3-3η is a novel regulator of parkin ubiquitin-ligase
2003
2003
Direct production of reactive oxygen species from aggregating proteins and peptides implicated in the pathogenesis of neurodegenerative diseases.
The deposition of abnormal protein fibrils is a prominent pathological feature of many different ‘protein conformational… 
2003
2003
Parkin mutations and early onset parkinsonism.
  • K. Morrison
  • Brain : a journal of neurology
  • 2003
  • Corpus ID: 21098908
Several recent articles have considered novel therapies in Parkinson’s disease, ranging from controlled trials of cell… 
1989
1989
Therapeutic efficacy of a novel transdermal delivery system for (+)-PHNO in parkinsonian squirrel monkeys.
undoubtedly explain a long term effect over receptor sites (which may be dopaminergic or calcium receptors) and/or over the…