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PAK3 protein, human

Known as: p21-Activated Protein Kinase 3, PAK-3, p21-Activated Kinase 3 
Serine/threonine-protein kinase PAK 3 (559 aa, ~62 kDa) is encoded by the human PAK3 gene. This protein is involved in the phosphorylation-dependent… Expand
National Institutes of Health

Papers overview

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2017
2017
p21-activated kinases (PAKs) are important effectors of the Rho family GTPases and has been implicated in cytoskelestal… Expand
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2015
2015
Significance Precise choreography of AMPA-type glutamate receptor (AMPAR) movements within neurons is critical for brain function… Expand
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2014
2014
Ischemic conditions reduce the activity of the p21-activated kinase (Pak1) resulting in increased arrhythmic activity. Triggered… Expand
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2013
2013
BACKGROUND  Hypertensive patients with large blood pressure variability (BPV) have aggravated target organ damage. Because the… Expand
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2012
2012
The calcium/calmodulin-dependent kinase II (CaMKII) participates with Ras to Raf-1 activation, and it is necessary for activation… Expand
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2011
2011
Microtubules are dynamic structures that must elongate, disassemble, and be cleaved into smaller pieces for proper neuronal… Expand
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Highly Cited
2007
Highly Cited
2007
The p21-activated kinase 3 (PAK3) is one of the recently identified genes for which mutations lead to nonsyndromic mental… Expand
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Highly Cited
2005
Highly Cited
2005
Mutations in the Pak3 gene lead to nonsyndromic mental retardation characterized by selective deficits in cognition. However, the… Expand
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Highly Cited
2000
Highly Cited
2000
Several guanine nucleotide exchange factors for the Rho family of GTPases that induce activation by exchanging GDP for GTP have… Expand
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Highly Cited
1995
Highly Cited
1995
The PAK family of protein kinases has been suggested as a potential target of the Cdc42 and Rac GTPases based on studies in vitro… Expand
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