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P2X receptor

 
National Institutes of Health

Papers overview

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2018
2018
ATP is the native agonist for cell-surface ligand-gated P2X receptor (P2XR) cation channels. The seven mammalian subunits (P2X1–7… Expand
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2018
2018
ABSTRACT Neuroinflammation is one of the mechanisms leading to neurodegenerative brain damage induced by chronic alcohol (ethanol… Expand
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2016
2016
P2X receptors are a group of homo/hetero-trimeric membrane protein complexes with an integral ion channel that opens upon… Expand
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2016
2016
BackgroundRetinal ganglion cell (RGC) soma death is a consequence of optic nerve damage, including in optic neuropathies like… Expand
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Review
2013
Review
2013
The occupancy of the orthosteric ligand binding sites of P2X receptor (P2XR) channels causes the rapid opening of a small cation… Expand
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2012
2012
AIM To examine whether the ob/ob mouse model of obesity is accompanied by enteric nervous system abnormalities such as altered… Expand
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Highly Cited
2011
Highly Cited
2011
Among purinergic P2X receptor (P2XR) channels, the P2X7R exhibits the most complex gating kinetics; the binding of orthosteric… Expand
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2011
2011
Objective: Cannabinoids play an important role in the suppression of proinflammatory cytokine production in the periphery and… Expand
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Highly Cited
2008
Highly Cited
2008
Background: Irritable bowel syndrome (IBS) is a common gastrointestinal disorder characterised by abdominal pain and bloating in… Expand
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Highly Cited
2003
Highly Cited
2003
Purinergic receptor stimulation has potential therapeutic effects for cystic fibrosis (CF). Thus, we explored roles for P2Y and… Expand
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