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P2X receptor

National Institutes of Health

Papers overview

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2018
2018
ATP is the native agonist for cell-surface ligand-gated P2X receptor (P2XR) cation channels. The seven mammalian subunits (P2X1–7… Expand
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2016
2016
BackgroundRetinal ganglion cell (RGC) soma death is a consequence of optic nerve damage, including in optic neuropathies like… Expand
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Review
2013
Review
2013
Transcripts and/or proteins of P2X receptor (P2XR) subunits have been found in virtually all mammalian tissues. Generally more… Expand
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Review
2013
Review
2013
Adenosine 5-triphosphate (ATP) is omnipresent in biology. It is therefore no surprise that organisms have evolved multifaceted… Expand
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Review
2013
Review
2013
The occupancy of the orthosteric ligand binding sites of P2X receptor (P2XR) channels causes the rapid opening of a small cation… Expand
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Review
2011
Review
2011
P2X receptor (P2XR) is a family of the ATP-gated ion channel family and can permeabilize the plasma membrane to small cations… Expand
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Highly Cited
2011
Highly Cited
2011
Among purinergic P2X receptor (P2XR) channels, the P2X7R exhibits the most complex gating kinetics; the binding of orthosteric… Expand
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2011
2011
Objective: Cannabinoids play an important role in the suppression of proinflammatory cytokine production in the periphery and… Expand
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Highly Cited
2008
Highly Cited
2008
Background: Irritable bowel syndrome (IBS) is a common gastrointestinal disorder characterised by abdominal pain and bloating in… Expand
Highly Cited
2003
Highly Cited
2003
Purinergic receptor stimulation has potential therapeutic effects for cystic fibrosis (CF). Thus, we explored roles for P2Y and… Expand