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extracellular ATP-gated cation channel activity

Known as: purinoceptor, purinoreceptor 
Enables the transmembrane transfer of a cation by a channel that opens when extracellular ATP has been bound by the channel complex or one of its… Expand
National Institutes of Health

Papers overview

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Review
2019
Review
2019
Ion channels play fundamental roles in both excitable and non-excitable tissues and therefore constitute attractive drug targets… Expand
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Review
2018
Review
2018
The P2RX7 receptor is a unique member of a family of extracellular ATP (eATP)-gated ion channels expressed in immune cells, where… Expand
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2015
2015
Background Duchenne muscular dystrophy (DMD) is the most common inherited muscle disease, leading to severe disability and death… Expand
2010
2010
Mammalian P2X receptors contain 10 conserved cysteine residues in their ectodomains, which form five disulfide bonds (SS1-5… Expand
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Highly Cited
2002
Highly Cited
2002
Extracellular nucleotides can activate a common purinoceptor mediating various cell responses. In this study we report that… Expand
1999
1999
The effects of purinoceptor subtypes on hippocampal extracellular serotonin levels were determined by using in vivo microdialysis… Expand
Highly Cited
1995
Highly Cited
1995
The P2Y1 purinoceptor cloned from chick brain (Webb, T. et al (1993) FEBS Lett., 324, 219-225) is a 362 amino acid, 41 kDa… Expand
1995
1995
Binding to PTH to its cell surface receptor activates both adenylyl cyclase and phospholipase-C, leading to elevation of… Expand
Review
1993
Review
1993
The present knowledge of voltage‐ and ligand‐activated ion channels of cultured microglial cells is described and its relevance… Expand
1984
1984
1 The inhibitory effects of a range of natural and synthetic derivatives of adenosine on the antigen‐induced release of histamine… Expand