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P-TEFb-cap methyltransferase complex

Known as: P-TEFb-Pcm1 complex, P-TEFb-Pcm1 complex location, P-TEFb-cap methyltransferase complex location 
A protein complex that is formed by the association of positive transcription elongation factor complex b (P-TEFb) with the mRNA capping… Expand
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Brd4 is a double bromodomain-containing protein that binds preferentially to acetylated chromatin. It belongs to the BET… Expand
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Highly Cited
2005
Highly Cited
2005
  • Z. Yang, J. Yik, +4 authors Qiang Zhou
  • Molecular cell
  • 2005
  • Corpus ID: 25239828
The cyclinT1/Cdk9 heterodimer that constitutes core P-TEFb is generally presumed to be the transcriptionally active form for… Expand
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Highly Cited
2003
Highly Cited
2003
The positive transcriptional elongation factor b (P-TEFb), consisting of CDK9 and cyclin T, stimulates transcription by… Expand
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Highly Cited
2001
Highly Cited
2001
The human positive transcription elongation factor P-TEFb, consisting of a CDK9/cyclin T1 heterodimer, functions as both a… Expand
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Highly Cited
2001
Highly Cited
2001
  • S. Chao, D. Price
  • The Journal of Biological Chemistry
  • 2001
  • Corpus ID: 25333906
Flavopiridol (L86-8275, HMR1275) is a cyclin-dependent kinase (Cdk) inhibitor in clinical trials as a cancer therapy that has… Expand
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Highly Cited
2000
Highly Cited
2000
P-TEFb, a heterodimer of the kinase Cdk9 and cyclin T, was isolated as a factor that stimulates formation of productive… Expand
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Highly Cited
2000
Highly Cited
2000
Flavopiridol (L86-8275, HMR1275) is a cyclin-dependent kinase (Cdk) inhibitor that is in clinical trials as a cancer treatment… Expand
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Highly Cited
1997
Highly Cited
1997
P-TEFb is a key regulator of the process controlling the processivity of RNA polymerase II and possesses a kinase activity that… Expand
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Highly Cited
1997
Highly Cited
1997
To identify novel inhibitors of transcriptional activation by the HIV Tat protein, we used a combination of in vitro and in vivo… Expand
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Highly Cited
1995
Highly Cited
1995
Production of full-length runoff transcripts in vitro and functional mRNA in vivo is sensitive to the drug 5,6-dichloro-1-β-D… Expand
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