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Oxymetazoline

Known as: 3-[(4,5-dihydro-1H-Imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol, Oxymetazoline [Chemical/Ingredient], Oxymetozoline 
An imidazole derivative with direct acting sympathomimetic activity. Oxymetazoline binds to and activates alpha-2 adrenergic receptors. Upon nasal or… 
National Institutes of Health

Related topics

Related topics

26 relations

Broader (3)

Adrenergic alpha-AgonistsNasal DecongestantsSympathomimetics

Narrower (3)

AfrinOxymetazoline hydrochlorideVisine L.R.
ConjunctivitisDecreased Nasal and Sinus Secretions [PE]ImidazolinesIn Blood

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1998
Highly Cited
1998
Effects of Intrathecal α1- and α2-Noradrenergic Agonists and Norepinephrine on Locomotion in Chronic Spinal Cats
Chau, Connie, Hugues Barbeau, and Serge Rossignol. Effects of intrathecal α1- and α2-noradrenergic agonists and norepinephrine on… 
1998
1998
Presynaptic inhibition by noradrenaline of the EPSC evoked in neonatal rat sympathetic preganglionic neurons
Highly Cited
1994
Highly Cited
1994
Both alpha 1A- and alpha 2A-adrenoreceptor subtypes stimulate voltage-operated L-type calcium channels in rat portal vein myocytes. Evidence for two distinct transduction pathways.
1992
1992
Is the neuronal ATP release from guinea-pig vas deferens subject to α 2-adrenoceptor-mediated modulation?
Highly Cited
1988
Highly Cited
1988
Electrophysiological characterization of adrenoceptors in the rat dorsal hippocampus. I. Receptors mediating the effect of microiontophoretically applied norepinephrine
1986
1986
Alpha-adrenoceptor-mediated antinociception and sedation in the rat and dog
Highly Cited
1983
Highly Cited
1983
Spinal clonidine inhibits neural firing in locus coeruleus
Highly Cited
1974
Highly Cited
1974
Antinociceptive effects of some α-sympathomimetic agents
Highly Cited
1974
Highly Cited
1974
Influence of drugs with affinity for alpha-adrenoceptors on noradrenaline release by potassium, tyramine and dimethylphenylpiperazinium.
Highly Cited
1972
Highly Cited
1972
Hypothermic effect of alpha-sympathomimetic agents and their antagonism by adrenergic and cholinergic blocking drugs.
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