Oxonate
National Institutes of Health
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Background: Ficus Benghalensis (Moraceae) Plant Species are widely available in Asian regions and used extensively in the field…
Objective:To test the action of uricase to lower plasma urate in hyperuricemic rat model developed with oxonate. Methods…
5-Dimethylsulfamoyl-6,7-dichloro-2,3-dihydrobenzofuran-2-carboxyli c acid (S-8666) was studied as a possible new uricosuric…
In most mammals, uric acid is converted into allantoin by the enzyme uricase, which does not occur in man and apes. Thus, the…
Adjuvant arthritis in rat is inhibited by an oxonate diet, which increases uricemia. The inhibition is proportional to blood uric…
Adjuvant arthritis in rat is inhibited by an oxonate diet, which increases uricemia. The inhibition is proportional to blood uric…
To study the mechanism by which oxonate-induced hyperuricemia inhibits the development of adjuvant arthritis in the rat, we…
Adjuvant arthritis in rats is inhibited by oxonate and not by allopurinol. Pyrimidine metabolism seems not to be involved in the…
Urate oxidase is present in axenic Acanthamoeba sp. (Neff strain). The enzyme shows an absolute requirement for molecular oxygen…