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Oxolinic Acid

Known as: Oxolinic Acid [Chemical/Ingredient], 5-Ethyl-8-oxo-5,8-dihydro [1,3] dioxolo [4,5-g] quinoline-7-carboxylic acid, Acid, Oxolinic 
Synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.
National Institutes of Health

Related topics

Related topics

13 relations

Broader (3)

Anti-Bacterial AgentsAnti-Infective Agents, UrinaryTopoisomerase II Inhibitors

Narrower (3)

GramurinSodium Oxolinatemiloxacin
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
A europium- and terbium-coated magnetic nanocomposite as sorbent in dispersive solid phase extraction coupled with ultra-high performance liquid chromatography for antibiotic determination in meat…
Highly Cited
2008
Highly Cited
2008
Multi-residue determination of seven quinolones antibiotics in gilthead seabream using liquid chromatography-tandem mass spectrometry.
Highly Cited
2007
Highly Cited
2007
Molecular imprinting-based separation methods for selective analysis of fluoroquinolones in soils.
Highly Cited
2004
Highly Cited
2004
Determination and on-line clean-up of (fluoro)quinolones in bovine milk using column-switching liquid chromatography fluorescence detection.
Highly Cited
2002
Highly Cited
2002
Validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of 11 (fluoro)quinolone antibiotics in swine kidney.
Highly Cited
2000
Highly Cited
2000
Determination of quinolones in plasma samples by capillary electrophoresis using solid-phase extraction.
Highly Cited
1991
Highly Cited
1991
Fate and microbiological effects of furazolidone in a marine aquaculture sediment.
1989
1989
Improvement of chemical analysis of antibiotics. XVI. Simple and rapid determination of residual pyridonecarboxylic acid antibacterials in fish using a prepacked amino cartridge.
Highly Cited
1983
Highly Cited
1983
The effect of bacterial DNA gyrase inhibitors on DNA synthesis in mammalian mitochondria.
Highly Cited
1983
Highly Cited
1983
Inhibition of RNA synthesis by oxolinic acid is unrelated to average DNA supercoiling
Oxolinic acid reduced RNA synthesis rates whether chromosome supercoiling decreased, increased, or remained unchanged. Thus… 
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