Fate and microbiological effects of furazolidone in a marine aquaculture sediment.

@article{Samuelsen1991FateAM,
  title={Fate and microbiological effects of furazolidone in a marine aquaculture sediment.},
  author={O. Samuelsen and E. Solheim and B. Lunestad},
  journal={The Science of the total environment},
  year={1991},
  volume={108 3},
  pages={
          275-83
        }
}
Furazolidone is used in the treatment of bacterial diseases in farmed fish. During application a large proportion of the administered drug reaches the environment directly or via feces. The persistence and metabolism of furazolidone in sediment from a Norwegian salmon farm is described. Furazolidone, in contrast to oxytetracycline and oxolinic acid, is actively metabolized by microorganisms in the sediment. The main metabolite is 3-(4-cyano-2-oxobutylidene-amino)-2-oxazolidone. This is a well… Expand
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The metabolism of a widely used veterinary drug, N-(5-nitro-2-furfurylidene)-3-amino-2-oxazolidone (furazolidone) was investigated in vitro and in vivo. When the nitrofuran was incubated with milkExpand
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