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Osteoclasts
Known as:
Osteoclast
A large multinuclear cell associated with the BONE RESORPTION. An odontoclast, also called cementoclast, is cytomorphologically the same as an…
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National Institutes of Health
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Related topics
Related topics
18 relations
Bone Resorption
Bone Tissue
Bone and Bones
Connective and Soft Tissue
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Broader (3)
Cell of bone
Connective Tissue Cells
cell type
Narrower (2)
Odontoclasts
Pacman dysplasia
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2003
Review
2003
Osteoclast differentiation and activation
W. J. Boyle
,
W. S. Simonet
,
D. Lacey
Nature
2003
Corpus ID: 4428121
Osteoclasts are specialized cells derived from the monocyte/macrophage haematopoietic lineage that develop and adhere to bone…
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Review
2003
Review
2003
Genetic regulation of osteoclast development and function
S. Teitelbaum
,
F. Ross
Nature reviews genetics
2003
Corpus ID: 20745235
Osteoclasts are the principal, if not exclusive, bone-resorbing cells, and their activity has a profound impact on skeletal…
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Highly Cited
2002
Highly Cited
2002
The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation
K. Nakashima
,
Xin Zhou
,
+4 authors
B. Crombrugghe
Cell
2002
Corpus ID: 14030684
Review
2000
Review
2000
Bone resorption by osteoclasts.
S. Teitelbaum
Science
2000
Corpus ID: 21170507
Osteoporosis, a disease endemic in Western society, typically reflects an imbalance in skeletal turnover so that bone resorption…
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Review
1999
Review
1999
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families.
T. Suda
,
N. Takahashi
,
N. Udagawa
,
E. Jimi
,
M. Gillespie
,
T. Martin
Endocrine reviews
1999
Corpus ID: 12520836
Osteoblasts/stromal cells are essentially involved in osteoclast differentiation and function through cell-to-cell contact (Fig…
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Highly Cited
1999
Highly Cited
1999
RANK is essential for osteoclast and lymph node development.
W. Dougall
,
M. Glaccum
,
+15 authors
J. Schuh
Genes & Development
1999
Corpus ID: 21426492
The physiological role of the TNF receptor (TNFR) family member, RANK, was investigated by generating RANK-deficient mice. RANK…
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Highly Cited
1998
Highly Cited
1998
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL.
H. Yasuda
,
N. Shima
,
+13 authors
T. Suda
Proceedings of the National Academy of Sciences…
1998
Corpus ID: 6536301
Osteoclasts, the multinucleated cells that resorb bone, develop from hematopoietic cells of monocyte/macrophage lineage…
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Highly Cited
1998
Highly Cited
1998
Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation
D. Lacey
,
E. Timms
,
+21 authors
W. J. Boyle
Cell
1998
Corpus ID: 18333816
Highly Cited
1997
Highly Cited
1997
Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density
W. S. Simonet
,
D. Lacey
,
+27 authors
W. J. Boyle
Cell
1997
Corpus ID: 12162262
Highly Cited
1997
Highly Cited
1997
Targeted Disruption of Cbfa1 Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts
T. Komori
,
H. Yagi
,
+12 authors
T. Kishimoto
Cell
1997
Corpus ID: 7369413
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