Bone Resorption

Known as: Losses, Osteoclastic Bone, Osteoclastic Bone Losses, Resorptions, Bone 
The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the… (More)

Topic mentions per year

Topic mentions per year

1938-2017
0500100019382016

Papers overview

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Highly Cited
2010
Highly Cited
2010
The broad expression of the insulin receptor suggests that the spectrum of insulin function has not been fully described. A cell… (More)
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Highly Cited
2005
Highly Cited
2005
Bone remodelling, the mechanism by which vertebrates regulate bone mass, comprises two phases, namely resorption by osteoclasts… (More)
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Highly Cited
2000
Highly Cited
2000
Young adult males who cannot produce or respond to estrogen (E) are osteopenic, suggesting that E may regulate bone turnover in… (More)
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Highly Cited
1998
Highly Cited
1998
Cathepsin K is a recently identified lysosomal cysteine proteinase. It is abundant in osteoclasts, where it is believed to play a… (More)
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Highly Cited
1997
Highly Cited
1997
A novel secreted glycoprotein that regulates bone resorption has been identified. The protein, termed Osteoprotegerin (OPG), is a… (More)
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Highly Cited
1996
Highly Cited
1996
Vertebrates constantly remodel bone. The resorption of preexisting bone by osteoclasts and the formation of new bone by… (More)
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Highly Cited
1996
Highly Cited
1996
Increased bone turnover has been suggested as a potential risk factor for osteoporotic fractures. We investigated this hypothesis… (More)
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Highly Cited
1990
Highly Cited
1990
To examine the possible involvement of IL-6 in bone metabolism, a mouse osteoblastic cell line (MC3T3-E1) and primary osteoblast… (More)
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Highly Cited
1990
Highly Cited
1990
The mechanisms by which bone resorbing osteoclasts form and are activated by hormones are poorly understood. We show here that… (More)
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Highly Cited
1986
Highly Cited
1986
When leukocytes are exposed to mitogens or antigens in vitro, they release bone-resorbing activity into the culture supernatants… (More)
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