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Orphan Nuclear Receptor ROR-gammaT

Known as: Nuclear Receptor ROR-Gamma Isoform 2, Nuclear Receptor RORgamma(t), RORgT 
Nuclear receptor ROR-gamma T (497 aa, ~56 kDa) is encoded by the human RORC gene. This protein is involved in both ligand-dependent transcriptional… 
National Institutes of Health

Related topics

Related topics

24 relations
Biologic DevelopmentCell Differentiation processCell NucleusCell Proliferation

Broader (1)

Nuclear Receptor Subfamily 1, Group F, Member 3

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Modulation of hypoxia-signaling pathways by extracellular linc-RoR
ABSTRACT Resistance to adverse environmental conditions, such as hypoxia, contributes to the reduced efficacy of anticancer… 
Highly Cited
2012
Highly Cited
2012
The human long non-coding RNA-RoR is a p53 repressor in response to DNA damage
It is well known that upon stress, the level of the tumor suppressor p53 is remarkably elevated. However, despite extensive… 
Highly Cited
2012
Highly Cited
2012
A Universal Denoising Framework With a New Impulse Detector and Nonlocal Means
Impulse noise detection is a critical issue when removing impulse noise and impulse/Gaussian mixed noise. In this paper, we… 
Review
2010
Review
2010
Melatonin: a pleiotropic molecule regulating inflammation.
Highly Cited
2009
Highly Cited
2009
A Th17‐like developmental process leads to CD8+ Tc17 cells with reduced cytotoxic activity
Activation of naive CD8+ T cells with antigen in the absence of skewing cytokines triggers their differentiation into effector… 
Highly Cited
2008
Highly Cited
2008
IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype
Differentiation of murine T-helper (Th) 17 cells is induced by antigenic stimulation and the sequential action of the cytokines… 
Highly Cited
2008
Highly Cited
2008
DC activated via dectin-1 convert Treg into IL-17 producers
Th cells producing IL‐17 play a pro‐inflammatory role at mucosal surfaces. Treg at the same sites dampen inflammation and prevent… 
Highly Cited
2008
Highly Cited
2008
Critical role of ROR-γt in a new thymic pathway leading to IL-17-producing invariant NKT cell differentiation
Invariant natural killer T (iNKT) cells constitute a subpopulation of T cells that recognize glycolipids presented by CD1d… 
Highly Cited
2008
Highly Cited
2008
When does evolution optimize
Aim: To elucidate the role of the eco-evolutionary feedback loop in determining evolutionarily stable life histories, with… 
Review
2003
Review
2003
The role of the nuclear hormone receptor RORγt in the development of lymph nodes and Peyer's patches
Summary:  The nuclear hormone receptor retinoic acid‐related orphan receptor (ROR)γt is required for the development of lymph… 
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