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Organic Cation Transporter

Known as: Organic Cation Transport Protein 
Organic Cation Transporter proteins carry positively charged chemical substances containing covalently bound carbon atoms through solubility barriers… 
National Institutes of Health

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13 relations
Carrier ProteinsCellular MembraneHomo sapiensIntegral Membrane Proteins

Papers overview

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Highly Cited
2011
Highly Cited
2011
Paraquat neurotoxicity is mediated by the dopamine transporter and organic cation transporter-3
The herbicide paraquat (PQ) has increasingly been reported in epidemiological studies to enhance the risk of developing Parkinson… 
Highly Cited
2010
Highly Cited
2010
Selective Transport of Monoamine Neurotransmitters by Human Plasma Membrane Monoamine Transporter and Organic Cation Transporter 3
The plasma membrane monoamine transporter (PMAT) and organic cation transporter 3 (OCT3) are the two most prominent low-affinity… 
Highly Cited
2010
Highly Cited
2010
Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metformin
Objectives The goals of this study were to determine the role of organic cation transporter 3 (OCT3) in the pharmacological… 
Highly Cited
2009
Highly Cited
2009
Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin
Objective The goal of this study was to determine the effect of a genetic variant in the organic cation transporter 2 (OCT2… 
Highly Cited
2009
Highly Cited
2009
Distribution of organic cation transporter 3, a corticosterone‐sensitive monoamine transporter, in the rat brain
Organic cation transporter 3 (OCT3) is a high‐capacity, low‐affinity transporter that mediates bidirectional, sodium‐independent… 
Highly Cited
2007
Highly Cited
2007
Transport of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin by Human Organic Anion Transporter 3, Organic Anion Transporting Polypeptide 4C1, and Multidrug Resistance P-glycoprotein
Sitagliptin, a selective dipeptidyl peptidase 4 inhibitor recently approved for the treatment of type 2 diabetes, is excreted… 
Highly Cited
2002
Highly Cited
2002
Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences.
By systematic mutation screening of the polyspecific organic cation transporter hOCT1 (SLC22A1) in 57 Caucasians, 25 genetic… 
Highly Cited
1998
Highly Cited
1998
Identity of the Organic Cation Transporter OCT3 as the Extraneuronal Monoamine Transporter (uptake2) and Evidence for the Expression of the Transporter in the Brain*
We investigated the transport of cationic neurotoxins and neurotransmitters by the potential-sensitive organic transporter OCT3… 
Highly Cited
1998
Highly Cited
1998
Transport of Monoamine Transmitters by the Organic Cation Transporter Type 2, OCT2*
The recently cloned apical renal transport system for organic cations (OCT2) exists in dopamine-rich tissues such as kidney and… 
Highly Cited
1996
Highly Cited
1996
cDNA cloning and functional expression of a novel rat kidney organic cation transporter, OCT2.
A cDNA encoding a novel organic cation transporter, designated as OCT2 was isolated from the rat kidney. The rat OCT2 cDNA (2,205… 
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