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Organic Cation Transporter

Known as: Organic Cation Transport Protein 
Organic Cation Transporter proteins carry positively charged chemical substances containing covalently bound carbon atoms through solubility barriers… Expand
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Although metformin, a cationic agent for type II diabetes, shows its pharmacological effect in the liver, the drug is mainly… Expand
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Highly Cited
2004
Highly Cited
2004
Crohn disease is a chronic, inflammatory disease of the gastrointestinal tract. A locus of ∼250 kb at 5q31 (IBD5) was previously… Expand
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Highly Cited
2003
Highly Cited
2003
Rheumatoid arthritis is a common inflammatory disease with complex genetic components. We investigated the genetic contribution… Expand
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Highly Cited
2002
Highly Cited
2002
Renal excretion is an important elimination pathway for antiviral agents, such as acyclovir (ACV), ganciclovir (GCV), and… Expand
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Highly Cited
1999
Highly Cited
1999
In the present study, functional characteristics of organic cation transporter (OCTN)1, which was cloned as the pH-dependent… Expand
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Highly Cited
1998
Highly Cited
1998
We have isolated a cDNA from rat placenta which, when expressed heterologously, mediates the transport of a wide spectrum of… Expand
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Highly Cited
1998
Highly Cited
1998
Primary carnitine deficiency, because of a defect of the tissue plasma membrane carnitine transporters, causes critical symptoms… Expand
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Highly Cited
1998
Highly Cited
1998
We investigated the transport of cationic neurotoxins and neurotransmitters by the potential-sensitive organic transporter OCT3… Expand
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Highly Cited
1997
Highly Cited
1997
Polyspecific organic cation transporters in the liver mediate the elimination of a wide array of endogenous amines and… Expand
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Highly Cited
1997
Highly Cited
1997
cDNA for a novel proton/organic cation transporter, OCTN1, was cloned from human fetal liver and its transport activity was… Expand
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