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Opipramol

Known as: 1-Piperazineethanol, 4-(3-(5H-dibenz(b,f)azepin-5-yl)propyl)-, Opipramol [Chemical/Ingredient] 
A tricyclic antidepressant with actions similar to AMITRIPTYLINE.
National Institutes of Health

Related topics

Related topics

11 relations

Broader (2)

Adrenergic Uptake InhibitorsTricyclic Antidepressive Agents
In BloodOpipramol Hydrochlorideagonistsanalogs & derivatives

Narrower (1)

Insidon

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Efficacy of treatments for anxiety disorders: a meta-analysis
To our knowledge, no previous meta-analysis has attempted to compare the efficacy of pharmacological, psychological and combined… 
Highly Cited
2008
Highly Cited
2008
σ-1 Receptor Modulation of Acid-Sensing Ion Channel a (ASIC1a) and ASIC1a-Induced Ca2+ Influx in Rat Cortical Neurons
Acid-sensing ion channels (ASICs) are proton-gated cation channels found in peripheral and central nervous system neurons. The… 
Highly Cited
2006
Highly Cited
2006
Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: a multi-level, single-sample approach.
2005
2005
Combined pH/organic solvent gradient HPLC in analysis of forensic material.
2004
2004
Neuropharmacology of the anxiolytic drug opipramol, a sigma site ligand.
Although opipramol is structurally related to imipramine, it does not represent a tricyclic antidepressant drug as it does not… 
Highly Cited
2003
Highly Cited
2003
Kava-Kava extract LI 150 is as effective as Opipramol and Buspirone in Generalised Anxiety Disorder--an 8-week randomized, double-blind multi-centre clinical trial in 129 out-patients.
OBJECTIVE An 8-week randomized, reference-controlled, double-blind, multi-centre clinical trial investigated Kava-Kava LI 150 in… 
Highly Cited
2001
Highly Cited
2001
Opipramol for the Treatment of Generalized Anxiety Disorder: A Placebo-Controlled Trial Including an Alprazolam-Treated Group
Opipramol, a drug widely prescribed in Germany, is a tricyclic compound with no reuptake-inhibiting properties. However, it has… 
1994
1994
Purification and amino-terminal sequencing of the high affinity phenylalkylamine Ca2+ antagonist binding protein from guinea pig liver endoplasmic reticulum.
Highly Cited
1989
Highly Cited
1989
High affinity dextromethorphan binding sites in guinea pig brain. Effect of sigma ligands and other agents.
Dextromethorphan (DM), a non-narcotic antitussive, binds in the guinea pig brain to specific high- and low-affinity sites with Kd… 
1976
1976
Influence of tricyclic antidepressants on the adenylate cyclase-phosphodiesterase system in the rat cortex
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