Open Reading Frames

Known as: Coding Feature, ORF, Open Reading Frame 
A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop… (More)
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Type 2 diabetes, fuelled by the obesity epidemic, is an escalating worldwide cause of personal hardship and public cost. Diabetes… (More)
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Highly Cited
2009
Highly Cited
2009
Upstream ORFs (uORFs) are mRNA elements defined by a start codon in the 5' UTR that is out-of-frame with the main coding sequence… (More)
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Highly Cited
2008
Highly Cited
2008
Through alternative processing of pre-messenger RNAs, individual mammalian genes often produce multiple mRNA and protein isoforms… (More)
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Highly Cited
2007
Highly Cited
2007
Complete sets of cloned protein-encoding open reading frames (ORFs), or ORFeomes, are essential tools for large-scale proteomics… (More)
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Highly Cited
2005
Highly Cited
2005
We predict regulatory targets of vertebrate microRNAs (miRNAs) by identifying mRNAs with conserved complementarity to the seed… (More)
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Highly Cited
2004
Highly Cited
2004
Stress-induced eukaryotic translation initiation factor 2 (eIF2) alpha phosphorylation paradoxically increases translation of the… (More)
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Highly Cited
2002
Highly Cited
2002
We have determined how most of the transcriptional regulators encoded in the eukaryote Saccharomyces cerevisiae associate with… (More)
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Highly Cited
2000
Highly Cited
2000
The chloroplast genomes of most higher plants contain two giant open reading frames designated ycf1 and ycf2. In tobacco, ycf1… (More)
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Highly Cited
1997
Highly Cited
1997
We have developed a new system of chromosomal mutagenesis in order to study the functions of uncharacterized open reading frames… (More)
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Highly Cited
1993
Highly Cited
1993
lin-4 is essential for the normal temporal control of diverse postembryonic developmental events in C. elegans. lin-4 acts by… (More)
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