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Open Reading Frames
Known as:
Coding Feature
, ORF
, Open Reading Frame
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A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop…
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National Institutes of Health
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Related topics
Related topics
6 relations
Chromosomes
PPP1R17 gene
Structural gene
aspects of radiation effects
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Unassigned Reading Frames
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Analysis of protein-coding genetic variation in 60,706 humans
James Y. Zou
Nature
2016
Corpus ID: 4454417
Large-scale reference data sets of human genetic variation are critical for the medical and functional interpretation of DNA…
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Review
2012
Review
2012
Amyotrophic lateral sclerosis.
A. Ludolph
,
J. Brettschneider
,
Jochen H Weishaupt
Current opinion in neurology
2012
Corpus ID: 770132
PURPOSE OF REVIEW The field of amyotrophic lateral sclerosis (ALS) has seen a number of remarkable advances during recent years…
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Highly Cited
2005
Highly Cited
2005
Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets
B. P. Lewis
,
C. Burge
,
D. Bartel
Cell
2005
Corpus ID: 17316349
Highly Cited
2004
Highly Cited
2004
Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response
Phoebe D. Lu
,
H. Harding
,
D. Ron
The Journal of cell biology
2004
Corpus ID: 2882259
Stress-induced eukaryotic translation initiation factor 2 (eIF2) α phosphorylation paradoxically increases translation of the…
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Highly Cited
2003
Highly Cited
2003
Global analysis of protein expression in yeast
S. Ghaemmaghami
,
W. Huh
,
+5 authors
J. Weissman
Nature
2003
Corpus ID: 4344864
The availability of complete genomic sequences and technologies that allow comprehensive analysis of global expression profiles…
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Highly Cited
1998
Highly Cited
1998
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
T. Kitada
,
S. Asakawa
,
+6 authors
N. Shimizu
Nature
1998
Corpus ID: 4432261
Parkinson's disease is a common neurodegenerative disease with complex clinical features. Autosomal recessive juvenile…
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Highly Cited
1993
Highly Cited
1993
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
Rosalind C. Lee
,
R. Feinbaum
,
V. Ambros
Cell
1993
Corpus ID: 205020975
Highly Cited
1993
Highly Cited
1993
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
M. MacDonald
,
C. Ambrose
,
+55 authors
P. Harper
Cell
1993
Corpus ID: 802885
Highly Cited
1991
Highly Cited
1991
Adaptive protein evolution at the Adh locus in Drosophila
J. McDonald
,
M. Kreitman
Nature
1991
Corpus ID: 205024070
PROTEINS often differ in amino-acid sequence across species. This difference has evolved by the accumulation of neutral mutations…
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Review
1987
Review
1987
An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs.
M. Kozak
Nucleic acids research
1987
Corpus ID: 32829771
5'-Noncoding sequences have been compiled from 699 vertebrate mRNAs. (GCC) GCCA/GCCATGG emerges as the consensus sequence for…
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