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Negative regulation of mitosis by the fission yeast protein phosphatase ppa2.
Ppa2 is the genetic locus controlling okadaic acid sensitivity, and evidence that ppa2+ negatively controls the entry into mitosis, possibly through the regulation of cdc2 tyrosine phosphorylation, is presented.
Molecular cloning of a rat 49-kDa TBP-interacting protein (TIP49) that is highly homologous to the bacterial RuvB.
It is suggested that TIP49, isolated from rat liver nuclear extracts, is a putative ATP-dependent DNA helicase.
A calcineurin-like gene ppb1+ in fission yeast: mutant defects in cytokinesis, cell polarity, mating and spindle pole body positioning.
The ppb1+ gene appears to be involved in cytokinesis, mating, transport, nuclear and spindle pole body positioning, and cell shape, and double-mutant analysis indicated that it had a function related to that of two other phosphatases, type 1-like dis2 and 2A-like ppa2.
Molecular cloning of a novel 120-kDa TBP-interacting protein.
- S. Yogosawa, Y. Makino, T. Yoshida, T. Kishimoto, M. Muramatsu, T. Tamura
- BiologyBiochemical and biophysical research…
- 13 December 1996
A 120-kD protein, termed TBP-interacting protein 120 (TIP120), was purified from rat liver nuclear extracts and exhibited sequence similarity to that of Drosophila TAF80, which was shown to bind directly to TBP.
Cloning the cDNA for a New Human Zinc Finger Protein Defines a Group of Closely Related Krüppel-like Transcription Factors*
Findings indicate that UKLF and CPBP/Zf9 represent a distinct subgroup of closely related Krüppel-like activators of transcription, which is lost when the highly conserved amino-terminal segment is deleted.
Isolation and characterization of the fission yeast protein phosphatase gene ppe1+ involved in cell shape control and mitosis.
- M. Shimanuki, N. Kinoshita, H. Ohkura, T. Yoshida, T. Toda, M. Yanagida
- BiologyMolecular biology of the cell
- 1 March 1993
The isolated fission yeast putative protein serine/threonine phosphatase gene designated ppe1+ may play a role in cell morphogenesis and mitosis by either regulating or being regulated by these multicopy suppressor gene products, and double mutants ppe2-ppa2 and ppe 1-pck1 are lethal at the permissive temperature.
Structures of the rat proteasomal ATPases: determination of highly conserved structural motifs and rules for their spacing.
- Y. Makino, S. Yogosawa, T. Tamura
- Biology, ChemistryBiochemical and biophysical research…
- 27 March 1996
Findings suggest a common function of the rat proteasomal ATPases in ATP-dependent RNA/DNA unwinding and four conserved motifs that are characteristic of a large family of ATP- dependent RNA/ DNA helicases.
Heterogeneous nuclear RNA‐ribonucleoprotein F binds to DNA via an oligo(dG)‐motif and is associated with RNA polymerase II
- T. Yoshida, K. Kokura, Y. Makino, V. Ossipow, T. Tamura
- Biology, ChemistryGenes to cells : devoted to molecular & cellular…
- 1 December 1999
The heterogeneous nuclear ribonucleoprotein F (hnRNP‐F) is one of the constituents of the splicing‐related hnRNP complex. Recent studies suggest that pre‐mRNA modification and splicing factors are…
Sister-chromatid separation and protein dephosphorylation in mitosis.