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Octreotide

Known as: Octreotide [Chemical/Ingredient], D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hyroxymethyl)propyl]-L-cysteinamide, Cyclic (2->7)-disulfide, D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol Cyclic (2->7)-Disulfide 
A synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. Octreotide is a more… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Cysteine protease cathepsins have traditionally been considered as lysosome-restricted proteases that mediate proteolysis of… Expand
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Highly Cited
2010
Highly Cited
2010
PURPOSE Metastatic carcinoid is an incurable malignancy whose symptoms, such as diarrhea and flushing, can be debilitating and… Expand
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Highly Cited
2008
Highly Cited
2008
PURPOSE Evaluate the activity of everolimus (RAD001) in combination with octreotide long-acting repeatable (LAR) in patients with… Expand
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Review
2004
Review
2004
Various tumours, classically specified as either neuroendocrine or non-neuroendocrine, contain high numbers of somatostatin… Expand
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Highly Cited
2002
Highly Cited
2002
Background—Circulating levels of interleukin-6 (IL-6) and tumor necrosis factor-&agr; (TNF-&agr;) are elevated in diabetic… Expand
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Highly Cited
2001
Highly Cited
2001
Abstract. The somatostatin analogue [DOTA0,Tyr3]octreotate has a nine-fold higher affinity for the somatostatin receptor subtype… Expand
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Highly Cited
1999
Highly Cited
1999
The aim of the study was to verify the effects of the administration of an inhibitor of the release of endogenous vasodilators… Expand
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Review
1997
Review
1997
OBJECTIVE This study was conducted to determine whether the perioperative administration of octreotide decreases the incidence of… Expand
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Highly Cited
1996
Highly Cited
1996
 
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Highly Cited
1992
Highly Cited
1992
Though morbidity and mortality rates following pancreatic resection have improved in recent years, they are still around 35% and… Expand
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