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Octreotide

Known as: Octreotide [Chemical/Ingredient], D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hyroxymethyl)propyl]-L-cysteinamide, Cyclic (2->7)-disulfide, D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol Cyclic (2->7)-Disulfide 
A synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. Octreotide is a more… 
National Institutes of Health

Related topics

Related topics

43 relations

Narrower (21)

(177lutetium-DOTA(O)Tyr3)octreotate111In-DOTA-TOC111indium-DOTA, Tyr(3)-octreotate3-Tyr-octreotide
1 ML Octreotide 0.1 MG/ML InjectionAcromegalyAdenomaIn Blood

Broader (3)

Antineoplastic Agents, HormonalGastrointestinal AgentsSomatostatin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Telotristat etiprate, a novel serotonin synthesis inhibitor, in patients with carcinoid syndrome and diarrhea not adequately controlled by octreotide.
Serotonin produced by neuroendocrine tumors is believed to be a principal cause of the diarrhea in carcinoid syndrome. We… 
Highly Cited
2006
Highly Cited
2006
Leukotriene C4 induces TGF-beta1 production in airway epithelium via p38 kinase pathway.
Cysteinyl leukotrienes (CysLTs) play an important role in the pathogenesis of airway remodeling. We investigated the interaction… 
Highly Cited
2001
Highly Cited
2001
Somatostatin receptors on peripheral primary afferent terminals: inhibition of sensitized nociceptors
Highly Cited
1999
Highly Cited
1999
Detection of glutathione in the human brain in vivo by means of double quantum coherence filtering
The feasibility of selective in vivo detection of glutathione (l‐γ‐glutamyl‐l‐cysteinyl‐glycine, GSH) in the human brain by means… 
Highly Cited
1994
Highly Cited
1994
Intestinal vessels express a high density of somatostatin receptors in human inflammatory bowel disease.
Highly Cited
1990
Highly Cited
1990
Entamoeba histolytica: correlation of the cytopathic effect of virulent trophozoites with secretion of a cysteine proteinase.
Highly Cited
1989
Highly Cited
1989
Spectroscopic studies of isopenicillin N synthase. A mononuclear nonheme Fe2+ oxidase with metal coordination sites for small molecules and substrate.
The nonheme iron oxidase isopenicillin N synthase catalyzes the formation of two new internal bonds in the tripeptide delta-(L… 
Highly Cited
1986
Highly Cited
1986
Truncated atrial natriuretic peptide analogs. Comparison between receptor binding and stimulation of cyclic GMP accumulation in cultured vascular smooth muscle cells.
Highly Cited
1985
Highly Cited
1985
Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analogue inhibitors containing a novel analogue of statine.
Analogues of the renin octapeptide substrate were synthesized in which replacement of the scissile dipeptide with (3S,4S)-4-amino… 
Highly Cited
1977
Highly Cited
1977
Ternary complex formation between elongation factor Tu, GTP and aminoacyl-tRNA: an equilibrium study.
The equilibria between the elongation factor Tu-GTP complex (EF-Tu-GTP) from Escherichia coli and tyrosyl-tRNATyr from E. coli as… 
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