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BACKGROUND & AIMS
We previously established long-term culture conditions under which single crypts or stem cells derived from… Expand BACKGROUND
Selective inhibition of cyclooxygenase-2 (COX-2) may be associated with an increased risk of thrombotic events, but… Expand BACKGROUND
Selective cyclooxygenase-2 (COX-2) inhibitors have come under scrutiny because of reports suggesting an increased… Expand Phosphatidylinositol 3-kinases (PI3Ks) are lipid kinases that regulate signaling pathways important for neoplasia, including cell… Expand Development of malignant tumours is in part characterized by the ability of a tumour cell to overcome cell–cell adhesion and to… Expand BACKGROUND
There is growing evidence that faecal-occult-blood (FOB) screening may reduce colorectal cancer (CRC) mortality, but… Expand BACKGROUND/AIMS
Several clinical, epidemiological, and animal studies indicate that nonsteroidal anti-inflammatory drugs (NSAIDs… Expand Method of treating a wound or burn which comprises directly dressing its surface with non-woven fabric comprising staple fibers… Expand Tumorigenesis has long been thought to be a multistep process (Foulds, 1958); however, only recently has it become possible to… Expand Because most colorectal carcinomas appear to arise from adenomas, studies of different stages of colorectal neoplasia may shed… Expand