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In vitro 3D cancer models that provide a more accurate representation of disease in vivo are urgently needed to improve our… Expand Breast cancer resistance protein (BCRP) confers multidrug resistance to cancer cells against agents such as SN-38 (an active… Expand PURPOSE
Glyoxalase I (GLO1) is an enzyme that plays a role in the detoxification of methylglyoxal, a side-product of glycolysis… Expand OBJECTIVE
The objective of this study was to compare the efficacy of photoimmunoconjugates with cationic and anionic molecular… Expand The cyclin-dependent kinase inhibitor p21WAF1/CIP1/SD11 (p21) plays a crucial role in DNA repair, cell differentiation, and… Expand The integrins are a family of cell surface receptors which mediate cellular adhesion and signalling events. Our goal was to… Expand The objective of this investigation was to determine the efficacy of i.p. photodynamic therapy (PDT) against solid, multifocal… Expand A new xenograft model for human epithelial ovarian carcinoma with extensive intraperitoneal (i.p.) carcinomatosis as the… Expand Exposure of human ovarian tumor cell lines to cisplatin led to development of cell lines that exhibited increasing degrees of… Expand Intracellular thiols have been proposed as mediators of resistance to alkylating agents and cisplatin. As metallothionein is the… Expand