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OVCAR-5

An adenocarcinoma cell line established from the ascetic fluid of a 67 year old female patient with ovarian carcinoma.
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
CD133 and CXCR4 were evaluated in the NCI-60 cell lines to identify cancer stem cell rich populations. Screening revealed that… Expand
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Highly Cited
2012
Highly Cited
2012
Targeting Chk1 protein kinase can enhance the antitumor effects of radio- and chemotherapy. Recent evidence disclosed a role of… Expand
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Highly Cited
2012
Highly Cited
2012
Women with late-stage ovarian cancer usually develop chemotherapeutic-resistant recurrence. It has been theorized that a rare… Expand
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Highly Cited
2011
Highly Cited
2011
In vitro 3D cancer models that provide a more accurate representation of disease in vivo are urgently needed to improve our… Expand
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Highly Cited
2002
Highly Cited
2002
Breast cancer resistance protein (BCRP) confers multidrug resistance to cancer cells against agents such as SN-38 (an active… Expand
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2000
2000
OBJECTIVE The objective of this study was to compare the efficacy of photoimmunoconjugates with cationic and anionic molecular… Expand
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Highly Cited
2000
Highly Cited
2000
The cyclin-dependent kinase inhibitor p21WAF1/CIP1/SD11 (p21) plays a crucial role in DNA repair, cell differentiation, and… Expand
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1996
1996
The objective of this investigation was to determine the efficacy of i.p. photodynamic therapy (PDT) against solid, multifocal… Expand
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Highly Cited
1992
Highly Cited
1992
Exposure of human ovarian tumor cell lines to cisplatin led to development of cell lines that exhibited increasing degrees of… Expand
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Highly Cited
1990
Highly Cited
1990
Intracellular thiols have been proposed as mediators of resistance to alkylating agents and cisplatin. As metallothionein is the… Expand
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