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OVCAR-5
An adenocarcinoma cell line established from the ascetic fluid of a 67 year old female patient with ovarian carcinoma.
National Institutes of Health
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2017
2017
Abstract 4200: Targeting cancer stem cells in serous ovarian carcinoma using RP6530, a dual PI3k δ/γ inhibitor
S. Sneha
,
R. Nivetha
,
R. Nagare
,
S. Viswanadha
,
S. Vakkalanka
,
T. Ganesan
2017
Corpus ID: 79486775
Ovarian cancer is one of the most lethal gynecological malignancies as most patients are diagnosed at an advanced stage and have…
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2016
2016
Abstract 4821: The WEE1 inhibitor AZD-1775 has synergic activity with trabectedin or lurbinectedin in ovarian cancer cells
S. Uboldi
,
L. Carrassa
,
R. Frapolli
,
P. Ubezio
,
E. Erba
,
M. D’Incalci
2016
Corpus ID: 78382007
AZD-1775 is a small molecule that selectively inhibits the tyrosine kinase WEE1, with a reported antineoplastic activity in…
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2015
2015
Proteomic Identification of Mediators Implicated in the Metastatic Progression of Ovarian Cancer
Natasha Musrap
2015
Corpus ID: 79256611
Ovarian cancer (OvCa) is the leading cause of death among gynecological malignancies, and is characterized by peritoneal…
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2014
2014
Multi-Functional Polymer Vesicles: Applications in Chemotherapy and Photodynamic Therapy
Nimil Sood
2014
Corpus ID: 137875609
The field of drug delivery is rapidly expanding to bridge the gap between novel drugs that are created and their effective entry…
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2013
2013
Treatment with Paclitaxel Orotate and Carboxyamidotriazole Orotate in SC-Implanted OVCAR-5 Human Ovarian Tumor Xenografts
R. Karmali
,
Y. Maxuitenko
,
G. Gorman
2013
Corpus ID: 72447327
Background: Paclitaxel (PTX) is approved for the treatment of refractory ovarian cancer and breast cancer, but is problematic due…
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2013
2013
Abstract A39: FAK inhibitors VS-6063 and VS-4718 preferentially target ovarian cancer stem cells
V. Kolev
,
Q. Wright
,
+4 authors
J. Pachter
2013
Corpus ID: 84698918
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that orchestrates cell signaling through integrins and growth…
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2013
2013
Abstract 236: Pharmacological and genetic inhibition of FAK attenuates cancer stem cell function in vitro and in vivo.
V. Kolev
,
Q. Wright
,
+5 authors
J. Pachter
2013
Corpus ID: 75954663
Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC Focal adhesion kinase (FAK) is a cytoplasmic…
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2012
2012
In vitro cytotoxicity, antimicrobial, and metal-chelating activity of triterpene saponins from tea seed grown in Kangra valley, India
R. Joshi
,
Swati Sood
,
+9 authors
A. Gulati
Medicinal Chemistry Research
2012
Corpus ID: 253633631
This study was undertaken to isolate and characterize saponins from seeds of Camellia sinensis. Four triterpene saponins S1, S2…
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2010
2010
Cancer esearch apeutics , Targets , and Chemical Biology 7 as a Molecular Target for Therapy in an In vitro R ee-Dimensional Model for Ovarian Cancer
N. Rahmanzadeh
,
P. Rai
,
+4 authors
T. Hasan
2010
Corpus ID: 207907245
r Res; 70( geting molecular markers and pathways implicated in cancer cell growth is a promising avenue for deng effective…
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2009
2009
CHARACTERIZATION OF SYNERGISTIC EFFECT OF IODODEOXYURIDINE AND CLOFARABINE IN CISPLATIN-RESISTANT OVARIAN CANCER CELLS By
A. Prakash
,
X. Bo
,
co-chair
,
José R. Fernández
,
K. Braunewell
,
J. Thottassery
2009
Corpus ID: 44238370
Epithelial ovarian cancer (EOC) is the most common gynecological cancer and the fifth most frequent cause of cancer deaths in…
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