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OTX1 gene

Known as: ORTHODENTICLE, DROSOPHILA, HOMOLOG OF, 1, OTX1, orthodenticle homeobox 1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
OTX1 Contributes to Hepatocellular Carcinoma Progression by Regulation of ERK/MAPK Pathway
Orthodenticlehomeobox 1 (OTX1) overexpression had previously been associated with the progression of several tumors. The present… 
2009
2009
Expression of the brain transcription factor OTX1 occurs in a subset of normal germinal-center B cells and in aggressive Non-Hodgkin Lymphoma.
The roles in brain development. Previous studies have shown the association between OTX2 and OTX1 with anaplastic and… 
Highly Cited
2006
Highly Cited
2006
The developing lamprey ear closely resembles the zebrafish otic vesicle: otx1 expression can account for all major patterning differences
The inner ear of adult agnathan vertebrates is relatively symmetric about the anteroposterior axis, with only two semicircular… 
Highly Cited
2005
Highly Cited
2005
Activin regulates luteinizing hormone beta-subunit gene expression through Smad-binding and homeobox elements.
LH beta-subunit (LHbeta), which is essential for ovulation and reproductive fitness, is synthesized specifically in pituitary… 
Highly Cited
2001
Highly Cited
2001
Otx1 null mutant mice show partial segregation of sensory epithelia comparable to lamprey ears
Abstract. We investigated the development of inner ear innervation in Otx1 null mutants, which lack a horizontal canal, between… 
Review
2000
Review
2000
Genetic and molecular roles of Otx homeodomain proteins in head development.
Highly Cited
1999
Highly Cited
1999
The TINS Lecture Understanding the roles of Otx1 and Otx2 in the control of brain morphogenesis
Highly Cited
1998
Highly Cited
1998
Transient dwarfism and hypogonadism in mice lacking Otx1 reveal prepubescent stage-specific control of pituitary levels of GH, FSH and LH.
Genetic and molecular approaches have enabled the identification of regulatory genes critically involved in determining cell… 
Highly Cited
1996
Highly Cited
1996
Otx1 function overlaps with Otx2 in development of mouse forebrain and midbrain
Background: We previously reported that the homozygous mutation of Otx2 gene, a mouse cognate of the Drosophila head gap gene… 
Highly Cited
1995
Highly Cited
1995
Expression pattern of two otx genes suggests a role in specifying anterior body structures in zebrafish.
We isolated two zebrafish sequences containing a homeobox related to orthodenticle (otd), a gene expressed in the developing head… 
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