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OTX1 gene

Known as: ORTHODENTICLE, DROSOPHILA, HOMOLOG OF, 1, OTX1, orthodenticle homeobox 1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Efficient generation of neural stem cell-like cells from adult human bone marrow stromal cells
Clonogenic neural stem cells (NSCs) are self-renewing cells that maintain the capacity to differentiate into brain-specific cell… 
Highly Cited
2001
Highly Cited
2001
Otx1 null mutant mice show partial segregation of sensory epithelia comparable to lamprey ears
Abstract. We investigated the development of inner ear innervation in Otx1 null mutants, which lack a horizontal canal, between… 
Highly Cited
1999
Highly Cited
1999
Cortical Neurons Require Otx1 for the Refinement of Exuberant Axonal Projections to Subcortical Targets
Highly Cited
1999
Highly Cited
1999
Otx1 and Otx2 activities are required for the normal development of the mouse inner ear.
The Otx1 and Otx2 genes are two murine orthologues of the Orthodenticle (Otd) gene in Drosophila. In the developing mouse embryo… 
Highly Cited
1999
Highly Cited
1999
The TINS Lecture Understanding the roles of Otx1 and Otx2 in the control of brain morphogenesis
Highly Cited
1999
Highly Cited
1999
Functional equivalency between Otx2 and Otx1 in development of the rostral head.
Mice have two Otx genes, Otx1 and Otx2. Prior to gastrulation, Otx2 is expressed in the epiblast and visceral endoderm. As the… 
Highly Cited
1998
Highly Cited
1998
Transient dwarfism and hypogonadism in mice lacking Otx1 reveal prepubescent stage-specific control of pituitary levels of GH, FSH and LH.
Genetic and molecular approaches have enabled the identification of regulatory genes critically involved in determining cell… 
Highly Cited
1998
Highly Cited
1998
Murine Otx1 and Drosophila otd genes share conserved genetic functions required in invertebrate and vertebrate brain development.
Despite the obvious differences in anatomy between invertebrate and vertebrate brains, several genes involved in the development… 
Highly Cited
1996
Highly Cited
1996
Xotx genes in the developing brain of Xenopus laevis
Highly Cited
1994
Highly Cited
1994
Otx1 and Otx2 define layers and regions in developing cerebral cortex and cerebellum
Within the cerebral and cerebellar cortices, neurons are organized in layers that segregate neurons with distinctive morphologies… 
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