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OPRL1 gene

Known as: kappa3-related opioid receptor, LC132 receptor-like, NOPr 
National Institutes of Health

Related topics

Related topics

1 relation
nociceptin receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Identification of a novel spiropiperidine opioid receptor-like 1 antagonist class by a focused library approach featuring 3D-pharmacophore similarity.
A focused library approach identifying novel leads to develop a potent ORL1 antagonist is described. Beginning from a compound… 
Highly Cited
2004
Highly Cited
2004
A novel series of piperidin-4-yl-1,3-dihydroindol-2-ones as agonist and antagonist ligands at the nociceptin receptor.
A series of N-(4-piperidinyl)-2-indolinones were discovered as a new structural class of nociceptin receptor (NOP) ligands… 
2003
2003
Cellular actions of opioids on periaqueductal grey neurons from C57B16/J mice and mutant mice lacking MOR‐1
Patch clamp recordings were made from periaqueductal grey (PAG) neurons in vitro to investigate the cellular actions of opioids… 
Highly Cited
2001
Highly Cited
2001
Actions of nociceptin/orphanin FQ and other prepronociceptin products on rat rostral ventromedial medulla neurons in vitro
1 Whole‐cell patch clamp recordings were made from rat rostral ventromedial medulla (RVM) neurons in vitro to investigate the… 
Highly Cited
2001
Highly Cited
2001
Characterization of opiates, neuroleptics, and synthetic analogs at ORL1 and opioid receptors.
Highly Cited
2000
Highly Cited
2000
High-affinity, non-peptide agonists for the ORL1 (orphanin FQ/nociceptin) receptor.
The discovery of 8-(5,8-dichloro-1,2,3,4-tetrahydro-naphthalen-2-yl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one, 1a, as a high… 
Highly Cited
1998
Highly Cited
1998
Sexual function in patients with penile carcinoma: a prospective study
Objectives: The aim of this study was to assess the incidence of incontinence and impotence in patients following total… 
Highly Cited
1997
Highly Cited
1997
Nociceptin-like immunoreactivity in the rat dorsal horn and inhibition of substantia gelatinosa neurons
Highly Cited
1997
Highly Cited
1997
Autoradiographic localization of [3H]nociceptin binding sites from telencephalic to mesencephalic regions of the mouse brain
Highly Cited
1997
Highly Cited
1997
Nociceptin, an Endogenous Ligand for the ORL1 Receptor, Decreases Cardiac Output and Total Peripheral Resistance in the Rat
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