OPN-305

Known as: Anti-TLR2 Monoclonal Antibody OPN-305 
A humanized immunoglobulin (Ig) G4 monoclonal antibody directed against toll-like receptor type 2 (TLR2), with potential anti-inflammatory and… Expand
National Institutes of Health

Papers overview

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2018
2018
INTRODUCTION: Innate immune sensors such as TLR2 are consistently overexpressed in bone marrow CD34+ cells from low risk MDS… Expand
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Review
2018
Review
2018
  • International reviews of immunology
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Innate immune system provides the first line of defense against pathogenic organisms. It has a varied and large collection of… Expand
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2016
2016
BackgroundGenetic vulnerability to environmental stressors is yet to be clarified in bipolar disorder (BD), a complex multisystem… Expand
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2016
2016
Background: Fine particulate matter (PM2.5) pollution is a major risk factor for cardiovascular diseases. Identifying modifiable… Expand
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2013
2013
Upregulation of Toll-like receptor 2 (TLR2) plays a critical role in inflammation associated with ischemia/reperfusion-induced… Expand
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2013
2013
OPN-305 is a humanized IgG4 monoclonal antibody against Tolllike receptor (TLR)2 being developed by Opsona Therapeutics. It is… Expand
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2013
2013
BACKGROUNDS The activation of Toll-like receptors (TLRs) may be an important event in the immune evasion of tumor cell. Recently… Expand
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2012
2012
BACKGROUND Toll-like receptor (TLR)-2 is an important mediator of innate immunity and ischemia/reperfusion-induced cardiac injury… Expand
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2012
2012
Toll-like receptors (TLRs) are important mediators of inflammatory responses by recognition of many pathogen-related molecules… Expand
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