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OPHN1 gene

Known as: OLIGOPHRENIN 1, ARHGAP41, Oligophrenin 1 Gene 
This gene plays a role in the mediation of GTP hydrolysis of Rho subfamily members.
National Institutes of Health

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Cytoskeletal ModelingOPHN1 wt AlleleOligophrenin-1Regulation of Cell Shape

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Exome sequencing of sporadic childhood‐onset schizophrenia suggests the contribution of X‐linked genes in males
Childhood‐onset schizophrenia (COS) is a rare and severe form of schizophrenia, defined as having an onset before the age of 13… 
2017
2017
Large in-frame intragenic deletion of OPHN1 in a male patient with a normal intelligence quotient score
Introduction The oligophrenin 1 gene (OPHN1, MIM 300127), localized in Xq12 and composed of 25 exons, encodes a RhoGTPase… 
2014
2014
Oligophrenin-1 Is Associated with Cell Adhesion and Migration in Prostate Cancer
Objective: We performed Escherichia coli ampicillin secretion trap (CAST) analysis in prostate cancer (PCa) to identify novel… 
Review
2013
Review
2013
Targeted Phosphotyrosine Profiling of Glycoprotein VI Signaling Implicates Oligophrenin-1 in Platelet Filopodia Formation
Objective—Platelet adhesion to subendothelial collagen is dependent on the integrin &agr;2&bgr;1 and glycoprotein VI (GPVI… 
Review
2009
Review
2009
Protumorigenic Role of HAPLN 1 and Its IgVDomain in Malignant Pleural Mesothelioma
Purpose:Tumor extracellular matrix (ECM) plays a crucial role in cancer progression mediating and transforming host-tumor… 
Review
2006
Review
2006
[Non-specific X-linked mental retardation].
INTRODUCTION Non-specific mental retardation is defined by the absence of somatic, neurological, biochemical or behavioural… 
2005
2005
Delineation of the clinical phenotype associated with OPHN1 mutations based on the clinical and neuropsychological evaluation of three families
Recent reports have demonstrated that mutations in the OPHN1 gene were responsible for a syndromic rather than non‐specific… 
2000
2000
Determination of the gene structure of human oligophrenin-1 and identification of three novel polymorphisms by screening of DNA from 164 patients with non-specific X-linked mental retardation.
1998
1998
Mind the GAP, Rho, Rab and GDI
Mental retardation is a common phenotype that is caused by defects in a large number of genes--the updated McKusick catalogue of… 
Review
1991
Review
1991
Non-specific X linked mental retardation.
Non-specific X linked mental retardation (MRX) is mental retardation in persons of normal physical appearance who have no… 
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