Mind the GAP, Rho, Rab and GDI

  title={Mind the GAP, Rho, Rab and GDI},
  author={Stylianos E. Antonarakis and Linda van Aelst},
  journal={Nature Genetics},
106 nature genetics volume 19 june 1998 Mental retardation is a common phenotype that is caused by defects in a large number of genes—the updated McKusick catalogue of genes and phenotypes (OMIM; http://www3.ncbi.nlm.nih.gov/ omim) responds with 828 entries when queried with “mental retardation”. Mapping the position of the corresponding loci, the first step towards cloning of the genes involved, is much easier on the X chromosome because of the ‘males only’affected pedigrees. This translates… CONTINUE READING


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