Oligophrenin-1

Known as: ARHGAP41, Oligophrenin 1, Rho GTPase-Activating Protein 41 
Oligophrenin-1 (802 aa, ~92 kDa) is encoded by the human OPHN1 gene. This protein plays a role in GTP hydrolysis.

Topic mentions per year

Topic mentions per year

1998-2017
02419982017

Papers overview

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2014
2014
Oligophrenin-1 (OPHN1) encodes for a Rho-GTPase-activating protein, important for dendritic morphogenesis and synaptic function… (More)
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2012
2012
The Rho GTPase activating protein (RhoGAP) Oligophrenin 1 (Ophn1) regulates numerous members of the Rho family that are involved… (More)
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2011
2011
Oligophrenin-1 regulates dendritic spine morphology in the brain. Mutations in the oligophrenin-1 gene (OPHN1) cause intellectual… (More)
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Highly Cited
2009
Highly Cited
2009
Oligophrenin-1 (OPHN1) encodes a Rho-GTPase-activating protein (Rho-GAP) whose loss of function has been associated with X-linked… (More)
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2009
2009
Neurons transmit information at chemical synapses by releasing neurotransmitters that are stored in synaptic vesicles (SVs) at… (More)
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2008
2008
Mutations in regulators and effectors of the Rho GTPases underlie various forms of mental retardation (MR). Among them… (More)
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2005
2005
BACKGROUND Mutations of oligophrenin 1, one of the first genes identified in nonspecific X-linked mental retardation (MRX), have… (More)
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2004
2004
Oligophrenin-1 (OPHN-1) gene disruption is known as responsible for so called "non-specific" X-linked mental retardation (MR… (More)
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2003
2003
Recent human genetic approaches showed that mutations in three genes encoding OPHN1, PAK3, and alphaPIX cause nonspecific X… (More)
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Highly Cited
1998
Highly Cited
1998
Primary or nonspecific X-linked mental retardation (MRX) is a heterogeneous condition in which affected patients do not have any… (More)
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