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OPC 41061

Known as: OPC-41061 
National Institutes of Health

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Broader (1)

tolvaptan

Papers overview

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2015
2015
A short term study and clinical application to evaluate the safety and effect of vasopressin 2 receptor antagonist (Tolvaptan, OPC-41061) in dogs
2014
2014
Effect of an Oral Vasopressin Receptor Antagonist (Tolvaptan, OPC-41061) in a Hydrocephalus Dog with Syndrome of Inappropriate Secretion of Antidiuretic Hormone(SIADH)
2007
2007
Tolvaptan (OPC-41061)
Arginin-Vasopressin (AVP), ein Nonapeptid, wird im Hypophysenhinterlappen sezerniert und stimuliert drei verschiedene Vasopressin… 
2007
2007
Effects of Nonpeptide Vasopressin V2 Antagonist Tolvaptan (OPC-41061) in Rats with Heart Failure
Review
2006
Review
2006
Vasopressin antagonists as aquaretic agents for the treatment of hyponatremia.
2005
2005
Fast Track Effectiveness of Vasopressin V 2 Receptor Antagonists OPC-31260 and OPC-41061 on Polycystic Kidney Disease Development in the PCK Rat
cAMP plays a major role in cystogenesis. Recent in vitro studies suggested that cAMP stimulates B-Raf/ERK activation and… 
Review
2004
Review
2004
Tolvaptan (Otsuka).
Otsuka is developing tolvaptan (OPC-41061), an orally active non-peptide vasopressin V2 antagonist, as a diuretic for the… 
2003
2003
Tolvaptan (OPC-41061), a V2 vasopressin receptor antagonist, protects against the decline in renal function observed with loop diuretic therapy
1999
1999
The preparation of soft gelatin capsules for a radioactive tracer study.
Clinical doses are developed for the oral coadministration of radiolabeled and nonlabeled forms of a poorly soluble… 
1998
1998
Safety and pharmacologic activity of the vasopressin V2 receptor antagonist OPC-41061 in healthy volunteers
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