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ONO 1301

Known as: ONO-1301 
National Institutes of Health

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Broader (1)

Pyridines

Papers overview

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2019
2019
ONO-1301 loaded nanocomposite scaffolds modulate cAMP mediated signaling and induce new bone formation in critical sized bone defect.
Recent studies on bone regeneration demonstrate the use of low cost and stable small molecules, which avoid the adverse effect… 
2015
2015
The Novel Prostaglandin I2 Mimetic ONO-1301 Escapes Desensitization in an Antiplatelet Effect Due to Its Inhibitory Action on Thromboxane A2 Synthesis in Mice
ONO-1301 [(E)-[5-[2-[1-phenyl-1-(3-pyridyl)methylidene-aminooxy]ethyl]-7,8-dihydronaphthalene-1-yloxy]acetic acid] is a novel… 
2014
2014
A sustained prostacyclin analog, ONO-1301, attenuates pancreatic fibrosis in experimental chronic pancreatitis induced by dibutyltin dichloride in rats.
2013
2013
Novel long-acting prostacyclin agonist (ONO-1301) with an angiogenic effect: promoting synthesis of hepatocyte growth factor and increasing cyclic AMP concentration via IP-receptor signaling.
The purpose of this study was to evaluate the angiogenic potency of ONO-1301, a novel prostacyclin agonist, using a murine sponge… 
2013
2013
Effect of antioxidants on the stability of ONO-1301, a novel long-acting prostacyclin agonist, loaded in PLGA microspheres
The purpose of this study was to investigate the physicochemical stability of ONO-1301 in poly(lactide-co-glycolide) microspheres… 
2012
2012
Single injection of ONO‐1301‐loaded PLGA microspheres directly after ischaemia reduces ischaemic damage in rats subjected to middle cerebral artery occlusion
Objectives  ONO‐1301 was developed as a novel long‐acting prostacyclin agonist with thromboxane synthase inhibitory activity. In… 
2012
2012
Sustained-release prostacyclin analog ONO-1301 ameliorates tubulointerstitial alterations in a mouse obstructive nephropathy model.
Tubulointerstitial injuries are crucial histological alterations that predict the deterioration of renal function in chronic… 
2011
2011
Preparation of ONO‐1301‐loaded poly(lactide‐co‐glycolide) microspheres and their effect on nerve conduction velocity
Objectives  The aim of this study was to prepare poly(lactide‐co‐glycolide) (PLGA) microspheres containing ONO‐1301, a novel long… 
2005
2005
Differential effect of prostaglandins E1 and E2 on lipopolysaccharide-induced adhesion molecule expression on human monocytes.
2003
2003
Unique Regulation Profile of Prostaglandin E1 on Adhesion Molecule Expression and Cytokine Production in Human Peripheral Blood Mononuclear Cells
In the present study, we examined the effects of prostaglandin E1 (PGE1) on the expression of intercellular adhesion molecule… 
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