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OKT4A monoclonal antibody

Known as: monoclonal antibody OKT4A, OKTcdr4a monoclonal antibody, monoclonal antibody OKTcdr4a 
National Institutes of Health

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Related topics

3 relations

Narrower (1)

IMUCLONE

Broader (1)

Monoclonal Antibodies
Orthoclone OKT(R)cdr4a

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1996
1996
Humanization and molecular modeling of the anti-CD4 monoclonal antibody, OKT4A.
OKT4A, a murine mAb that recognizes an epitope on the CD4 receptor, is a potent immunosuppressive agent in vitro and in a variety… 
Highly Cited
1990
Highly Cited
1990
Infection of monocytes by human immunodeficiency virus type 1 blocked by inhibitors of CD4-gp120 binding, even in the presence of enhancing antibodies
Infection of monocyte/macrophages (M/M) by a variety of viruses (including HIV-1) has been shown to be enhanced in the presence… 
1990
1990
Sulphoevernan, a polyanionic polysaccharide, and the narcissus lectin potently inhibit human immunodeficiency virus infection by binding to viral envelope protein.
Sulphoevernan is a sulphated alpha-1----3, 1----4 polyglucan (Mr 20,000) with a helical structure. This compound effectively… 
Highly Cited
1990
Highly Cited
1990
Prolonged survival of nonhuman primate renal allograft recipients treated only with anti-CD4 monoclonal antibody.
The immunosuppressive efficacy of the monoclonal antibody OKT4A reactive with human and monkey CD4 cells was evaluated in… 
Highly Cited
1989
Highly Cited
1989
HIV-1 GP120-mediated immune suppression and lymphocyte destruction in the absence of viral infection.
The magnitude of immunologic defects observed in HIV-1-infected individuals before the development of overt AIDS is… 
Highly Cited
1989
Highly Cited
1989
Human eosinophils express CD4 protein and bind human immunodeficiency virus 1 gp120
The CD4 glycoprotein, expressed on leukocytes belonging to subsets of T lymphocytes and to cells of monocyte/macrophage lineage… 
Highly Cited
1989
Highly Cited
1989
Human immunodeficiency virus glycoprotein (gp120) induction of monocyte arachidonic acid metabolites and interleukin 1.
This study reports on the direct effect of the envelope glycoprotein (gp120) of the human immunodeficiency virus type 1 (HIV-1… 
Highly Cited
1988
Highly Cited
1988
Binding region for human immunodeficiency virus (HIV) and epitopes for HIV-blocking monoclonal antibodies of the CD4 molecule defined by site-directed mutagenesis.
The binding region for human immunodeficiency virus (HIV) and epitopes for a panel of HIV-blocking anti-CD4 monoclonal antibodies… 
Highly Cited
1988
Highly Cited
1988
Location and chemical synthesis of a binding site for HIV-1 on the CD4 protein.
The human immunodeficiency virus type 1 (HIV-1) uses the CD4 protein as a receptor for infection of susceptible cells. A… 
Highly Cited
1982
Highly Cited
1982
Possible involvement of the OKT4 molecule in T cell recognition of class II HLA antigens. Evidence from studies of cytotoxic T lymphocytes specific for SB antigens
A recently described HLA gene, SB, which maps between GLO and HLA-DR, codes for Ia-like molecules that are similar to but… 
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