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OCA-983

National Institutes of Health

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Carbapenems

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2006
2006
Simultaneous hydrogenolysis of p-nitrobenzyl esters and carbamates side-chains in the THF 1beta-carbapenem OCA-983 in biphasic media.
Deprotection of p-nitrobenzyl esters and valyl carbamates in carbapenem CL 192,276 produced the active compound OCA-983 in… 
2001
2001
THF carbapenems. Wyeth Ayerst.
CL-191121 is one of three new tetrahydrofuranyl (THF) carbapenems, which possess stability to renal dihydropeptidase and beta… 
1999
1999
Convergent syntheses of oral THF 1beta-methylcarbapenems.
Convergent syntheses of oral THF 1beta-methylcarbapenems 4 (OCA-983) and 5 starting from M2-phosphate 1 were developed. Reaction… 
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