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Nkx-3.1 protein

Known as: Homeobox Protein NK-3 Homolog A, Homeobox Protein Nkx-3.1, NK3 Transcription Factor Homolog A 
Homeobox protein Nkx-3.1 (234 aa, ~26 kDa) is encoded by the human NKX3-1 gene. This protein plays a role in the modulation of transcription.
National Institutes of Health

Related topics

Related topics

8 relations
DNA-Binding ProteinsGenes, RegulatorHomeodomain ProteinsNKX3-1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
MP68-10 HOXB13 EXPRESSION AND ITS ROLE IN PROSTATE CANCER PROGRESSION AND NEUROENDOCRINE DIFFERENTIATION
INTRODUCTION AND OBJECTIVES: HOXB13 expression is involved in normal prostate development, is a known regulator of androgen… 
Review
2017
Review
2017
NKL homeobox gene activities in hematopoietic stem cells, T-cell development and T-cell leukemia
T-cell acute lymphoblastic leukemia (T-ALL) cells represent developmentally arrested T-cell progenitors, subsets of which… 
2017
2017
New developments in prostate cancer screening using a novel cancer-specific, non-PSA biomarker assay derived from autoantibody signatures
Background: Over diagnosis and overtreatment of indolent prostate cancer (PC) is a serious health issue. There is an unmet… 
2017
2017
Transcriptional regulation of the Nkx3.1 gene in prostate luminal stem cell specification and cancer initiation via its 3' genomic region.
NK3 homeobox 1 (Nkx3.1), a transcription factor expressed in the prostate epithelium, is crucial for maintaining prostate cell… 
2016
2016
4C-seq revealed long-range interactions of a functional enhancer at the 8q24 prostate cancer risk locus
Genome-wide association studies (GWAS) have identified >100 independent susceptibility loci for prostate cancer, including the… 
2015
2015
A comprehensive molecular characterization of aggressive variant prostate cancer (PC).
149 Background: Unusually aggressive PC behavior is linked to small cell carcinoma (SCC) morphology. We observed SCC clinical… 
2012
2012
Transcriptional Activation of Prostate Specific Homeobox Gene NKX3-1 in Subsets of T-Cell Lymphoblastic Leukemia (T-ALL)
Homeobox genes encode transcription factors impacting key developmental processes including embryogenesis, organogenesis, and… 
Review
2012
Review
2012
Loss of NKX3-1 as a potential marker for an increased risk of occult lymph node metastasis and poor prognosis in oral squamous cell carcinoma.
The prognosis of oral squamous cell carcinoma (OSCC) is significantly dependent on the existence of cervical lymph… 
2010
2010
A seminal finding for prostate cancer?
A subgroup of luminal cells in the prostate gland of the mouse are resistant to apoptosis induced by androgen withdrawal and can… 
1984
1984
Multiple L double-stranded RNA species of Saccharomyces cerevisiae: evidence for separate encapsidation
The L double-stranded (ds) RNA component of Saccharomyces cerevisiae may contain up to three dsRNA species, each with a distinct… 
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