Nivocasan

Known as: (5R)-N-((2S,3S)-2-(Fluoromethyl)-2-hydroxy-5-oxo-tetrahydrofuran-3-yl)-3-(isoquinolin- 1-yl)-5-(1-methylethyl)-4,5-dihydroisoxazole-5-carboxamide, 5-isoxazolecarboxamide, N-((2S,3S)-2-(fluoromethyl)tetrahydro-2-hydroxy-5-oxo-3-furanyl)-4,5-dihydro-3-(1-isoquinolinyl)-5-(1-methylethyl)-, (5R)-

National Institutes of Health

Papers overview

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2019

2019

Auranofin Inhibits RANKL-Induced Osteoclastogenesis by Suppressing Inhibitors of κB Kinase and Inflammasome-Mediated Interleukin-1β Secretion

Hyun Young KimK. KimMyungyeon KimH. KimKwang Youl LeeK. Kang
Oxidative Medicine and Cellular Longevity
2019
Corpus ID: 145995863

Osteoporosis is a degenerative metabolic disease caused by an imbalance between osteogenesis and osteoclastogenesis. Increased…

2013

2013

Combined effects of an antioxidant and caspase inhibitor on the reversal of hepatic fibrosis in rats

D. Y. KimSook In Chung K. Han
Apoptosis
2013
Corpus ID: 254250359

We sought to determine the hepatic fibrosis-reversal effects upon simultaneous administration of lithospermate B (LAB), an anti…