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MDM2 and p53 polymorphisms are associated with the development of hepatocellular carcinoma in patients with chronic hepatitis B virus infection.
MDM2 SNP 309 and p53 Arg72Pro are associated with the early development of HCC in Korean patients with chronic HBV infection.
Sorafenib or placebo plus TACE with doxorubicin-eluting beads for intermediate stage HCC: The SPACE trial.
Performance of Transient Elastography for the Staging of Liver Fibrosis in Patients with Chronic Hepatitis B: A Meta-Analysis
Transient elastography can be performed with good diagnostic accuracy for quantifying liver fibrosis in patients with CHB, according to a meta-analysis.
A Liver Stiffness Measurement-Based, Noninvasive Prediction Model for High-Risk Esophageal Varices in B-Viral Liver Cirrhosis
LSPS is a reliable, noninvasive method for detection of HEVs and patients with LSPS<3.5 may avoid endoscopy safely, whereas those withLSPS>5.5 should be considered for appropriate prophylactic treatments.
Complete response at first chemoembolization is still the most robust predictor for favorable outcome in hepatocellular carcinoma.
Risk assessment of hepatitis B virus–related hepatocellular carcinoma development using liver stiffness measurement (FibroScan)
The data suggest that LSM could be a useful predictor of HCC development in patients with chronic hepatitis B and together with old age, male sex, heavy alcohol consumption, serum albumin, and hepatitis B e antigen positivity, patients with a higher LSM were at a significantly greater risk of H CC development.
Validation of FIB‐4 and comparison with other simple noninvasive indices for predicting liver fibrosis and cirrhosis in hepatitis B virus‐infected patients
Noninvasive tests to determine the degree of hepatic fibrosis have been developed and can be used to optimize management and predict long‐term clinical courses in patients with chronic hepatitis B (CHB).
New Automated Hepatitis C Virus (HCV) Core Antigen Assay as an Alternative to Real-Time PCR for HCV RNA Quantification
- Yongjung Park, Jong-Han Lee, B. Kim, D. Y. Kim, K. Han, Hyon-Suk Kim
- Biology, MedicineJournal of Clinical Microbiology
- 29 March 2010
An automated hepatitis C virus (HCV) antigen (Ag) assay was evaluated with clinical samples and revealed that these two tests were highly correlated, suggesting that this assay could be an alternative test to quantitative reverse transcription-PCR.
Lower Incidence of Hepatocellular Carcinoma and Cirrhosis in Hepatitis C Patients with Sustained Virological Response by Pegylated Interferon and Ribavirin
Non-cirrhotic patients with SVR had significantly lower risk of progression to cirrhosis compared with patients with non-SVR, and SVR was related to a reduced risk of HCC development.
Sarcopenia is associated with significant liver fibrosis independently of obesity and insulin resistance in nonalcoholic fatty liver disease: Nationwide surveys (KNHANES 2008‐2011)
Sarcopenia is associated with significant liver fibrosis in subjects with NAFLD, and the association is independent of obesity and insulin resistance.