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Nimorazole

Known as: Morpholine, 4-(2-(5-nitro-1H-imidazol-1-yl)ethyl)-, Nitrimidazine, Nimorazole [Chemical/Ingredient] 
A water soluble, 5-nitroimidazole compound with antibacterial and potential radiosensitizing activity. As an oxygen mimetic, nimorazole induces free… 
National Institutes of Health

Related topics

Related topics

11 relations

Broader (1)

Antitrichomonal Agents

Narrower (3)

EsclamaK-1900Naxogin
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Overcoming Radioresistance: Small Molecule Radiosensitisers and Hypoxia-activated Prodrugs.
2018
2018
DAHANCA 10 - Effect of darbepoetin alfa and radiotherapy in the treatment of squamous cell carcinoma of the head and neck. A multicenter, open-label, randomized, phase 3 trial by the Danish head and…
Review
2006
Review
2006
Design of hypoxia-targeting drugs as new cancer chemotherapeutics.
The tumor microenvironment is now recognized as a major factor that influences not only the response to conventional anti-cancer… 
1991
1991
The potential of using hyperthermia to eliminate radioresistant hypoxic cells.
Highly Cited
1988
Highly Cited
1988
Structure-activity relationships of the inhibition of human placental aromatase by imidazole drugs including ketoconazole.
1985
1985
Effects of glutathione depletion using buthionine sulphoximine on the cytotoxicity of nitroaromatic compounds in mammalian cells in vitro.
Highly Cited
1982
Highly Cited
1982
A comparative investigation of nimorazole and misonidazole as hypoxic radiosensitizers in a C3H mammary carcinoma in vivo.
The hypoxic cell radiosensitizing properties of nimorazole have been investigated in a C3H mammary carcinoma transplanted to the… 
Highly Cited
1982
Highly Cited
1982
Nitroimidazoles as anaerobic electron acceptors for xanthine oxidase.
1982
1982
Studies on the induction of sex-linked recessive lethal mutations in Drosophila melanogaster by nitroheterocyclic compounds.
1975
1975
The mutagenic action of nitroimidazoles. II. Effects of 2-nitroimidazoles.
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