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1 Lancet. 2003 Sep 20;362(9388):933-40. Five compared with six fractions per week of conventional radiotherapy of squamous-cell… Expand Abstract Purpose/Objective. A phase II clinical trial evaluating the feasibility and outcome of treating locally advanced head… Expand PURPOSE
To validate the predictive impact of a hypoxia gene expression classifier in identifying patients with head and neck… Expand Radiosensitizers are intended to enhance tumour cell killing while having much less effect on normal tissues. Some drugs target… Expand BACKGROUND
The concentration of osteopontin (SPP1) in plasma is associated with tumour hypoxia. The DAHANCA 5 trial found that… Expand Hypoxia develops in tumors because of a less ordered, often chaotic, and leaky vascular supply compared with that in normal… Expand BACKGROUND
Although head and neck cancer can be cured by radiotherapy, the optimum treatment time for locoregional control is… Expand PURPOSE
A multicenter randomized and balanced double-blind trial with the objective of assessing the efficacy and tolerance of… Expand Hypoxic modification by nitroimidazoles has been explored in a large number of clinical studies. Nine different drugs… Expand Summary In L URIA AND D ELBRUCK'S fluctuation test, with streptomycin-resistance and streptomycin-dependence as markers, certain… Expand