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Nimorazole

Known as: Morpholine, 4-(2-(5-nitro-1H-imidazol-1-yl)ethyl)-, Nitrimidazine, Nimorazole [Chemical/Ingredient] 
A water soluble, 5-nitroimidazole compound with antibacterial and potential radiosensitizing activity. As an oxygen mimetic, nimorazole induces free… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
1 Lancet. 2003 Sep 20;362(9388):933-40. Five compared with six fractions per week of conventional radiotherapy of squamous-cell… Expand
Highly Cited
2015
Highly Cited
2015
Abstract Purpose/Objective. A phase II clinical trial evaluating the feasibility and outcome of treating locally advanced head… Expand
Highly Cited
2012
Highly Cited
2012
PURPOSE To validate the predictive impact of a hypoxia gene expression classifier in identifying patients with head and neck… Expand
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Review
2007
Review
2007
  • P. Wardman
  • Clinical oncology (Royal College of Radiologists…
  • 2007
  • Corpus ID: 34738474
Radiosensitizers are intended to enhance tumour cell killing while having much less effect on normal tissues. Some drugs target… Expand
Highly Cited
2005
Highly Cited
2005
BACKGROUND The concentration of osteopontin (SPP1) in plasma is associated with tumour hypoxia. The DAHANCA 5 trial found that… Expand
Review
2005
Review
2005
Hypoxia develops in tumors because of a less ordered, often chaotic, and leaky vascular supply compared with that in normal… Expand
Highly Cited
2003
Highly Cited
2003
BACKGROUND Although head and neck cancer can be cured by radiotherapy, the optimum treatment time for locoregional control is… Expand
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Highly Cited
1998
Highly Cited
1998
PURPOSE A multicenter randomized and balanced double-blind trial with the objective of assessing the efficacy and tolerance of… Expand
Highly Cited
1994
Highly Cited
1994
Hypoxic modification by nitroimidazoles has been explored in a large number of clinical studies. Nine different drugs… Expand
Highly Cited
1974
Highly Cited
1974
Summary In L URIA AND D ELBRUCK'S fluctuation test, with streptomycin-resistance and streptomycin-dependence as markers, certain… Expand