Nimorazole

Known as: Morpholine, 4-(2-(5-nitro-1H-imidazol-1-yl)ethyl)-, Nitrimidazine, Nimorazole [Chemical/Ingredient] 
A water soluble, 5-nitroimidazole compound with antibacterial and potential radiosensitizing activity. As an oxygen mimetic, nimorazole induces free… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
  • venlig hilsen, Jenny, Anne-Mette, Stine og Jakob
  • 2016
1 Lancet. 2003 Sep 20;362(9388):933-40. Five compared with six fractions per week of conventional radiotherapy of squamous-cell… (More)
Is this relevant?
Highly Cited
2012
Highly Cited
2012
PURPOSE To validate the predictive impact of a hypoxia gene expression classifier in identifying patients with head and neck… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
Highly Cited
2010
Highly Cited
2010
BACKGROUND HPV/p16-positive head and neck cancers (HNSCC) show superior response to radiotherapy, compared with virus-negative… (More)
Is this relevant?
Review
2007
Review
2007
Radiosensitizers are intended to enhance tumour cell killing while having much less effect on normal tissues. Some drugs target… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
BACKGROUND The concentration of osteopontin (SPP1) in plasma is associated with tumour hypoxia. The DAHANCA 5 trial found that… (More)
Is this relevant?
2005
2005
Sanazole (AK-2123, 3-nitrotriazole derivative, N1-(3-methoxypropyl)-2-(3-nitro-1 H-1,2,4-triazol-1-yl)acetamide) and nimorazole… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
2003
2003
BACKGROUND AND PURPOSE Causes of failure of radiotherapy in squamous cell carcinoma of the head and neck probably include… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
PURPOSE A multicenter randomized and balanced double-blind trial with the objective of assessing the efficacy and tolerance of… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Hypoxic modification by nitroimidazoles has been explored in a large number of clinical studies. Nine different drugs… (More)
Is this relevant?
1983
1983
The pharmacokinetics of the hypoxic radio-sensitizer nimorazole were studied in 19 individuals after single oral doses of between… (More)
  • table I
  • figure 1
  • table II
  • figure 2
  • figure 3
Is this relevant?